HitPredict

Interactor 1: ZBT43 (O43298)
Zinc finger and BTB domain-containing protein 43 (Zinc finger and BTB domain-containing protein 22B) (Zinc finger protein 297B) (ZnF-x)
Gene: ZBTB43

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein deacylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26949739
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 467 Hs			1 482
+	Hs
		1109976 ZBTB9_HUMAN (3-446): 1.33e-70: 233: 27.04		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Mm
		148633 ZBT7A_MOUSE (374-467): 7.54e-35: 138: 26.80		HDAC1_MOUSE (1-482): 0: 672: 99.38
+	Hs
		334555 ZBT7A_HUMAN (374-467): 2.26e-34: 137: 26.80		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		334574 ZBT7A_HUMAN (374-467): 2.26e-34: 137: 26.80		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1109886 BCL6B_HUMAN (398-465): 6.42e-24: 105: 32.86		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1109973 NACC2_HUMAN (8-143): 4.1e-22: 101: 41.14		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1368041 NACC2_HUMAN (8-143): 4.1e-22: 101: 41.14		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Mm
		148704 ZBT7B_MOUSE (399-466): 2.7e-17: 86.2: 28.57		HDAC1_MOUSE (1-482): 0: 672: 99.38
+	Mm
		1000015 ZBT7B_MOUSE (399-466): 2.7e-17: 86.2: 28.57		HDAC2_MOUSE (1-478): 0: 664: 85.71
+	Hs
		1347174 ZN461_HUMAN (363-446): 1.26e-10: 65.5: 41.18		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		188137 ZBT7A_HUMAN (374-467): 2.26e-34: 137: 26.80		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Mm
		1353899 ZBT7C_MOUSE (377-467): 1.98e-31: 129: 27.96		Q9JM08_MOUSE (9-434): 0: 568: 57.71
+	Hs
		188345 NACC1_HUMAN (7-147): 5.27e-22: 100: 42.28		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		180129 ZBT7B_HUMAN (399-466): 1.9e-17: 86.6: 28.57		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Mm
		313126 ZBT7B_MOUSE (399-466): 2.7e-17: 86.2: 28.57		HDAC3_MOUSE (9-434): 0: 574: 58.18
+	Hs
		1281686 ZSCA2_HUMAN (84-180): 3.07e-18: 89.5: 11.34		HDAC8_HUMAN (32-371): 2.55e-139: 407: 43.11