HitPredict

Interactor 1: B2L11 (O43521)
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Gene: BCL2L11

Interactor 2: BAK (Q16611)
Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)
Gene: BAK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23374347
Identification Methods surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bclx_interact
Common GO terms GO:0001782 - B cell homeostasis
GO:0002262 - myeloid cell homeostasis
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
and 9 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 198
Hs

1 211
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Mm
+ Rn
+ Mm
+ Hs
+ Rn
+ Mm
+ Rn
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 11Aug2025