Protein: B2L11
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)

Gene: B2L11, BCL2L11
Organism: Homo sapiens
Interactions: 104
UniProt ID: O43521

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0001782 - B cell homeostasis
GO:0001822 - kidney development
GO:0002262 - myeloid cell homeostasis
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

219622

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

32

16

Small-scale

0.992

High

219621

B2CL1
Bcl-2-like protein 1

23

17

Small-scale

0.990

High

219594

BCL2
Apoptosis regulator Bcl-2

18

17

Small-scale

0.987

High

219650

B2CL2
Bcl-2-like protein 2

11

17

Small-scale

0.977

High

219620

BAX
Apoptosis regulator BAX

7

17

Small-scale

0.962

High

219632

B2LA1
Bcl-2-related protein A1

4

16

Small-scale

0.888

High

219659

B2L10
Bcl-2-like protein 10

4

0

Small-scale

0.870

High

219616

DYL1
Dynein light chain 1, cytoplasmic

7

2

Small-scale

0.742

High

219666

FBW1A
F-box/WD repeat-containing protein 1A

6

2

Small-scale

0.730

High

219572

B2L11
Bcl-2-like protein 11

2

0

Small-scale

0.716

High

219665

FBW1B
F-box/WD repeat-containing protein 11

5

2

Small-scale

0.714

High

219654

DYL2
Dynein light chain 2, cytoplasmic

4

2

Small-scale

0.686

High

219664

UBQL2
Ubiquilin-2

4

0

Small-scale

0.655

High

219600

EDNRA
Endothelin-1 receptor

3

0

High-throughput

0.638

High

219610

MTHR
Methylenetetrahydrofolate reductase

3

0

High-throughput

0.638

High

219642

RHPN2
Rhophilin-2

3

0

High-throughput

0.638

High

219602

MK03
Mitogen-activated protein kinase 3

2

1

Small-scale

0.624

High

219633

BAK
Bcl-2 homologous antagonist/killer

1

17

Small-scale

0.618

High

219637

KLH10
Kelch-like protein 10

2

0

High-throughput

0.602

High

219646

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

0

High-throughput

0.602

High

219661

CISH
Cytokine-inducible SH2-containing protein

2

1

Small-scale

0.584

High

219609

PEX19
Peroxisomal biogenesis factor 19

2

0

High-throughput

0.580

High

219592

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.577

High

67114

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

2

0

Small-scale

0.559

High

219597

CCNB1
G2/mitotic-specific cyclin-B1

2

0

Small-scale

0.559

High

219606

HSP74
Heat shock 70 kDa protein 4

2

0

Small-scale

0.559

High

219627

CUL2
Cullin-2

2

0

Small-scale

0.559

High

219617

RACK1
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.554

High

219612

MK08
Mitogen-activated protein kinase 8

1

3

Small-scale

0.550

High

219611

MAGAB
Melanoma-associated antigen 11

1

0

High-throughput

0.549

High

219648

NDRG1
Protein NDRG1

1

0

Small-scale

0.537

High

219605

1433B
14-3-3 protein beta/alpha

1

1

Small-scale

0.536

High

219630

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.513

High

219596

MIF
Macrophage migration inhibitory factor

1

0

Small-scale

0.506

High

219593

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.493

High

219604

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

Small-scale

0.484

High

219655

AURKB
Aurora kinase B

1

3

High-throughput

0.481

High

219591

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

219619

BTK
Tyrosine-protein kinase BTK

1

0

Small-scale

0.480

High

219651

BAD
Bcl2-associated agonist of cell death

1

0

Small-scale

0.479

High

169834

AURKA
Aurora kinase A

1

3

Small-scale

0.479

High

219577

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

Small-scale

0.479

High

219595

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

1

Small-scale

0.479

High

219598

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.479

High

219603

MK01
Mitogen-activated protein kinase 1

1

1

Small-scale

0.479

High

161764

RIOK3
Serine/threonine-protein kinase RIO3

1

0

High-throughput

0.460

High

219576

VATG1
V-type proton ATPase subunit G 1

1

0

High-throughput

0.460

High

219656

FEM1C
Protein fem-1 homolog C

1

0

High-throughput

0.460

High

219573

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

219580

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

219599

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

Small-scale

0.458

High

219608

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

219615

BID
BH3-interacting domain death agonist

1

0

Small-scale

0.458

High

219626

BIK
Bcl-2-interacting killer

1

0

Small-scale

0.458

High

219628

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

Small-scale

0.458

High

219631

ELOB
Elongin-B

1

0

Small-scale

0.458

High

219657

TRIM2
Tripartite motif-containing protein 2

1

2

Small-scale

0.457

High

219586

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

3

High-throughput

0.445

High

219587

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

3

High-throughput

0.445

High

219588

FIBG
Fibrinogen gamma chain

1

3

High-throughput

0.445

High

219663

MTCH1
Mitochondrial carrier homolog 1

1

1

High-throughput

0.445

High

219667

KLK5
Kallikrein-5

1

1

High-throughput

0.445

High

219670

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.445

High

219623

FGL1
Fibrinogen-like protein 1

1

3

High-throughput

0.439

High

219660

DLRB1
Dynein light chain roadblock-type 1

1

1

Small-scale

0.437

High

219575

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.426

High

219585

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.426

High

219649

EVPL
Envoplakin

1

0

High-throughput

0.426

High

219658

GOLP3
Golgi phosphoprotein 3

1

0

High-throughput

0.426

High

219578

SPB7
Serpin B7

1

3

High-throughput

0.407

High

219583

A1AT
Alpha-1-antitrypsin

1

2

High-throughput

0.407

High

219607

SPB5
Serpin B5

1

2

High-throughput

0.407

High

219613

KLK7
Kallikrein-7

1

1

High-throughput

0.407

High

219643

SPA12
Serpin A12

1

2

High-throughput

0.407

High

219641

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

3

0

High-throughput

0.347

High

219652

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

3

0

High-throughput

0.347

High

219634

S39AC
Zinc transporter ZIP12

3

0

High-throughput

0.345

High

219579

MTA2
Metastasis-associated protein MTA2

2

0

High-throughput

0.328

High

219614

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.328

High

219669

PCDBB
Protocadherin beta-11

2

0

High-throughput

0.328

High

219625

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

219640

DTX2
Probable E3 ubiquitin-protein ligase DTX2

2

0

High-throughput

0.316

High

219645

USBP1
Harmonin-binding protein USHBP1

2

0

High-throughput

0.316

High

67160

ZAR1L
Protein ZAR1-like

2

0

High-throughput

0.313

High

219639

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

0

High-throughput

0.279

Low

219662

GPC5D
G-protein coupled receptor family C group 5 member D

1

0

High-throughput

0.279

Low

219618

GTF2I
General transcription factor II-I

1

0

Small-scale

0.261

Low

219624

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

Small-scale

0.261

Low

219635

OTUD1
OTU domain-containing protein 1

1

0

Small-scale

0.249

Low

219644

CD302
CD302 antigen

1

0

Small-scale

0.249

Low

219653

GIMA5
GTPase IMAP family member 5

1

0

Small-scale

0.249

Low

219574

CATL2
Cathepsin L2

1

0

High-throughput

0.232

Low

219581

CERU
Ceruloplasmin

1

0

High-throughput

0.232

Low

219582

HPT
Haptoglobin

1

0

High-throughput

0.232

Low

219584

CO3
Complement C3

1

0

High-throughput

0.232

Low

219589

TTHY
Transthyretin

1

0

High-throughput

0.232

Low

219590

TRFE
Serotransferrin

1

0

High-throughput

0.232

Low

219601

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.232

Low

219629

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.232

Low

219636

DMKN
Dermokine

1

0

High-throughput

0.232

Low

219638

SBSN
Suprabasin

1

0

High-throughput

0.232

Low

219647

POF1B
Protein POF1B

1

0

High-throughput

0.232

Low

219668

PKP3
Plakophilin-3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025