HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: NHSL1 (Q5SYE7)
NHS-like protein 1
Gene: NHSL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.50	0.630

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 1610
+	Hs
		594018 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		NHSL1_HUMAN (1-1610): 1.18e-154: 515: 100.00
+	Hs
		222118 NCK2_HUMAN (1-380): 3.54e-95: 290: 100.00		NHS_HUMAN (69-1551): 1.43e-63: 241: 22.82
+	Hs
		594025 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		NHS_HUMAN (69-1551): 1.43e-63: 241: 22.82
+	Hs
		222100 NCK2_HUMAN (1-380): 3.54e-95: 290: 100.00		NHSL2_HUMAN (74-1160): 1.6e-48: 192: 12.64
+	Hs
		594014 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		NHSL2_HUMAN (74-1160): 1.6e-48: 192: 12.64
+	Hs
		222032 NCK2_HUMAN (1-380): 3.54e-95: 290: 100.00		PRC2A_HUMAN (345-1602): 1.02e-11: 72.6: 8.71
+	Hs
		594085 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		MINT_HUMAN (62-1144): 1.96e-16: 88: 10.61
+	Hs
		440773 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		MAGL2_HUMAN (111-1077): 5.45e-23: 109: 7.20
+	Hs
		319045 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		K0754_HUMAN (804-1337): 8.2e-20: 99.2: 10.24
+	Hs
		699836 P85A_HUMAN (166-379): 7.1e-25: 108: 16.36		MINT_HUMAN (62-1144): 1.96e-16: 88: 10.61
+	Hs
		463316 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		MUC1_HUMAN (463-1364): 1.37e-13: 78.3: 11.77
+	Hs
		557306 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		NCOA6_HUMAN (129-1586): 2.36e-16: 87.6: 7.83
+	Hs
		987833 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		PRG4_HUMAN (77-689): 1.95e-17: 91.1: 6.04
+	Hs
		463610 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		MICA3_HUMAN (635-1385): 4.9e-12: 73.7: 14.56
+	Hs
		987883 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		MINT_HUMAN (62-1144): 1.96e-16: 88: 10.61
+	Hs
		439935 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		MUC1_HUMAN (463-1364): 1.37e-13: 78.3: 11.77
+	Hs
		557066 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		MUC1_HUMAN (463-1364): 1.37e-13: 78.3: 11.77
+	Hs
		590268 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		MUC1_HUMAN (463-1364): 1.37e-13: 78.3: 11.77
+	Hs
		557438 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		CIC_HUMAN (133-967): 1.64e-10: 68.7: 8.13
+	Hs
		875616 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		PRC2A_HUMAN (345-1602): 1.02e-11: 72.6: 8.71