HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: NHSL2 (Q5HYW2)
NHS-like protein 2
Gene: NHSL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.578

Property	Details
Experiments	unassigned1304, 28514442, unassigned3799
Identification Methods	two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 1225
+	Hs
		594014 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		NHSL2_HUMAN (1-1225): 1.29e-132: 438: 100.00
+	Hs
		222118 NCK2_HUMAN (1-380): 3.54e-95: 290: 100.00		NHS_HUMAN (22-1187): 2.35e-22: 106: 11.87
+	Hs
		594025 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		NHS_HUMAN (22-1187): 2.35e-22: 106: 11.87
+	Hs
		222107 NCK2_HUMAN (1-380): 3.54e-95: 290: 100.00		NHSL1_HUMAN (91-1214): 2.49e-16: 87.1: 12.58
+	Hs
		594018 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		NHSL1_HUMAN (91-1214): 2.49e-16: 87.1: 12.58
+	Hs
		594085 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		MINT_HUMAN (120-1107): 2e-14: 80.9: 10.51
+	Hs
		66953 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		L37A2_HUMAN (318-1162): 1.08e-68: 256: 13.91
+	Hs
		215903 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		SYNJ1_HUMAN (711-1178): 1.3e-11: 71.7: 12.15
+	Hs
		1453436 ITSN2_HUMAN (5-273): 6.53e-36: 141: 19.27		DAPLE_HUMAN (669-1225): 2.84e-10: 67.4: 15.66
+	Hs
		319045 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		K0754_HUMAN (64-675): 7.82e-20: 98.6: 8.94
+	Hs
		215925 ITSN1_HUMAN (5-253): 2.96e-28: 119: 16.61		SYNJ1_HUMAN (711-1178): 1.3e-11: 71.7: 12.15
+	Hs
		699836 P85A_HUMAN (166-379): 7.1e-25: 108: 16.36		MINT_HUMAN (120-1107): 2e-14: 80.9: 10.51
+	Hs
		463811 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		DAPLE_HUMAN (669-1225): 2.84e-10: 67.4: 15.66
+	Hs
		440773 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		MAGL2_HUMAN (762-1215): 4.03e-10: 66.7: 8.24
+	Hs
		463610 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		MICA3_HUMAN (532-1174): 1.74e-09: 64.7: 16.49
+	Hs
		463316 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		MUC1_HUMAN (806-1220): 1.84e-09: 64.6: 8.43
+	Hs
		215893 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		SYNJ1_HUMAN (711-1178): 1.3e-11: 71.7: 12.15
+	Hs
		440738 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		MAGE1_HUMAN (826-1197): 3.04e-09: 63.4: 13.64
+	Hs
		439935 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		MUC1_HUMAN (806-1220): 1.84e-09: 64.6: 8.43
+	Hs
		557066 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		MUC1_HUMAN (806-1220): 1.84e-09: 64.6: 8.43