HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: NHS (Q6T4R5)
Actin remodeling regulator NHS (Congenital cataracts and dental anomalies protein) (Nance-Horan syndrome protein)
Gene: NHS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 1651
+	Hs
		222118 NCK2_HUMAN (1-376): 1.95e-92: 283: 68.24		NHS_HUMAN (1-1651): 4.99e-121: 421: 100.00
+	Hs
		594014 NCK1_HUMAN (1-377): 2.37e-99: 301: 100.00		NHSL2_HUMAN (429-1545): 1.49e-35: 150: 20.77
+	Hs
		222100 NCK2_HUMAN (1-376): 1.95e-92: 283: 68.24		NHSL2_HUMAN (429-1545): 1.49e-35: 150: 20.77
+	Hs
		594018 NCK1_HUMAN (1-377): 2.37e-99: 301: 100.00		NHSL1_HUMAN (186-1650): 4.94e-28: 125: 16.82
+	Hs
		222107 NCK2_HUMAN (1-376): 1.95e-92: 283: 68.24		NHSL1_HUMAN (186-1650): 4.94e-28: 125: 16.82
+	Hs
		594085 NCK1_HUMAN (1-377): 2.37e-99: 301: 100.00		MINT_HUMAN (715-1650): 1.19e-15: 85.8: 8.72
+	Hs
		593966 NCK1_HUMAN (1-377): 2.37e-99: 301: 100.00		ANK2_HUMAN (891-1627): 4.01e-09: 64: 15.52
+	Hs
		274251 ITSN2_HUMAN (7-85): 2.53e-12: 70.6: 24.05		ANR17_HUMAN (444-1418): 5.86e-38: 158: 11.44
+	Hs
		834224 CSK_HUMAN (186-375): 1.98e-33: 131: 26.18		CIC_HUMAN (32-1649): 1.56e-18: 95: 9.52
+	Hs
		590268 GRB2_HUMAN (3-61): 2.31e-17: 82.1: 28.81		MUC1_HUMAN (9-990): 7.12e-32: 138: 9.72
+	Hs
		987833 GRB2_HUMAN (3-61): 2.31e-17: 82.1: 28.81		PRG4_HUMAN (1017-1647): 3.57e-28: 126: 8.72
+	Hs
		557066 SRC_HUMAN (5-152): 5.68e-12: 68.8: 19.74		MUC1_HUMAN (9-990): 7.12e-32: 138: 9.72
+	Hs
		699836 P85A_HUMAN (241-376): 5.42e-23: 102: 19.57		MINT_HUMAN (715-1650): 1.19e-15: 85.8: 8.72
+	Hs
		1129687 SH3K1_HUMAN (56-207): 4.07e-09: 60.1: 17.53		MDC1_HUMAN (55-1196): 9.02e-25: 115: 10.04
+	Hs
		987883 GRB2_HUMAN (3-61): 2.31e-17: 82.1: 28.81		MINT_HUMAN (715-1650): 1.19e-15: 85.8: 8.72
+	Hs
		557438 SRC_HUMAN (5-152): 5.68e-12: 68.8: 19.74		CIC_HUMAN (32-1649): 1.56e-18: 95: 9.52
+	Hs
		1384267 SH3K1_HUMAN (56-207): 4.07e-09: 60.1: 17.53		PRR36_HUMAN (4-1019): 5.78e-20: 99.3: 10.77
+	Hs
		987550 GRB2_HUMAN (3-61): 2.31e-17: 82.1: 28.81		ANK2_HUMAN (891-1627): 4.01e-09: 64: 15.52
+	Hs
		1065097 ITK_HUMAN (3-138): 3.38e-11: 66.7: 21.01		SRRM2_HUMAN (17-1079): 1.01e-11: 72.7: 9.38
+	Hs
		1384308 SH3K1_HUMAN (56-207): 4.07e-09: 60.1: 17.53		SRRM2_HUMAN (17-1079): 1.01e-11: 72.7: 9.38