HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	35543156
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0060090 - molecular adaptor activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 540
+	Hs
		226817 SGTA_HUMAN (1-313): 4.33e-68: 216: 100.00		HUWE1_HUMAN (79-539): 2.9e-23: 106: 13.36
+	Bt
		94867 E1B7G3_BOVIN (52-239): 1.31e-38: 145: 24.87		Q2KHZ7_BOVIN (1-532): 1.39e-47: 174: 48.97
+	Hs
		208136 SGTB_HUMAN (1-311): 1.35e-54: 181: 57.24		PLXB1_HUMAN (78-332): 1.48e-10: 66.3: 19.62
+	Hs
		916681 PPP5_HUMAN (66-268): 8.29e-37: 139: 24.63		HUWE1_HUMAN (79-539): 2.9e-23: 106: 13.36
+	Dm
		1285855 Q9VH81_DROME (65-239): 2.37e-41: 152: 28.81		Q86CW5_DROME (96-512): 3.14e-18: 90.6: 12.61
+	Dm
		402278 Q9VH81_DROME (65-239): 2.37e-41: 152: 28.81		RPB1_DROME (131-506): 1.88e-11: 69.1: 12.31
+	Dm
		1475710 Q9VH81_DROME (65-239): 2.37e-41: 152: 28.81		Q9VPR2_DROME (60-417): 2.86e-10: 65.2: 11.20
+	Dm
		402273 Q9V3E9_DROME (83-226): 4.38e-40: 148: 30.56		RPB1_DROME (131-506): 1.88e-11: 69.1: 12.31
+	Hs
		185816 OGT1_HUMAN (83-284): 7.91e-21: 94.9: 15.76		HUWE1_HUMAN (79-539): 2.9e-23: 106: 13.36
+	Mm
		92770 PPP5_MOUSE (66-268): 9.17e-37: 139: 24.14		D3Z656_MOUSE (196-533): 9.1e-09: 60.6: 8.64
+	Hs
		731425 STIP1_HUMAN (85-259): 1.56e-19: 90.7: 23.96		HUWE1_HUMAN (79-539): 2.9e-23: 106: 13.36
+	Mm
		1274322 OGT1_MOUSE (83-284): 7.62e-21: 94.9: 15.76		HUWE1_MOUSE (108-539): 5.17e-18: 90.3: 13.89
+	Hs
		718565 CDC27_HUMAN (6-233): 1.22e-24: 106: 17.54		MDC1_HUMAN (79-450): 8.81e-11: 67.1: 13.06
+	Hs
		185700 OGT1_HUMAN (83-284): 7.91e-21: 94.9: 15.76		MDC1_HUMAN (79-450): 8.81e-11: 67.1: 13.06
+	Hs
		185866 OGT1_HUMAN (83-284): 7.91e-21: 94.9: 15.76		KMT2C_HUMAN (102-538): 1.41e-09: 63.3: 10.60
+	Hs
		731119 STIP1_HUMAN (85-259): 1.56e-19: 90.7: 23.96		SC24C_HUMAN (116-429): 9.68e-11: 66.7: 15.43