Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN
Interactor 2: GSH1 (P48506)
Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)
Gene: GCLC
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 0.60 | 0.584 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0006979 - response to oxidative stress GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0043524 - negative regulation of neuron apoptotic process and 1 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
