HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: MTNA (Q9BV20)
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)
Gene: MRI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 369
+	Hs
		226862 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		EI2BB_HUMAN (33-364): 8.62e-104: 311: 19.88
+	Hs
		1219364 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		MTNA_HUMAN (1-369): 1.06e-143: 413: 100.00
+	Hs
		228998 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		EI2BD_HUMAN (45-354): 1.51e-89: 280: 21.45
+	Hs
		227436 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		EI2BA_HUMAN (67-357): 1.68e-77: 242: 25.25
+	Hs
		474960 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		EI2BB_HUMAN (33-364): 8.62e-104: 311: 19.88
+	At
		1092463 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		MTNA_ARATH (2-347): 3.74e-114: 338: 56.86
+	At
		72040 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		B3H7H1_ARATH (120-364): 5.56e-70: 226: 25.00