Interactor 1: O46034 (O46034)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27)
Gene: Cbl
Interactor 2: EGFR (P04412)
Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo)
Gene: EGFR
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 0.60 | 0.692 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9121472, 28993397, 9178769, unassigned4 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, experimental interaction detection |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0007476 - imaginal disc-derived wing morphogenesis GO:1903688 - positive regulation of border follicle cell migration |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
