Interactor 1: ARHG7 (O55043)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (PAK-interacting exchange factor beta)
Gene: Arhgef7
Interactor 2: SHAN2 (Q9QX74)
SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (GKAP/SAPAP-interacting protein) (Proline-rich synapse-associated protein 1) (ProSAP1) (SPANK-3)
Gene: Shank2
Species: Rattus norvegicus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12626503 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDZ_6~betaPIX_CC, RhoGEF~SH3_2, SH3_2~SH3_2 |
| Common GO terms | GO:0005886 - plasma membrane GO:0030426 - growth cone GO:0043005 - neuron projection GO:0043025 - neuronal cell body |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025