Interactor 1: PSMA8 (Q8TAA3)
Proteasome subunit alpha-type 8 (Proteasome alpha 4 subunit) (Alpha4s) (Proteasome subunit alpha-type 7-like)
Gene: PSMA8

Interactor 2: PSB7 (Q99436)
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) (Proteasome subunit beta-2) (beta-2)
Gene: PSMB7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.921

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 17948026, unassigned3799
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pr_beta_C~Proteasome, Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 256
Hs

1 277
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+ Dm
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+ Af
+ Ph

Service provided by Combinatics, Japan

Last updated: 11Aug2025