Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: JMJD6 (Q6NYC1)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)
Gene: JMJD6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.759

The method score is based on:

Property Details
Experiments 28514442, 33961781, 21555454, 29176719, 32416067, 33567268, 30554943, 23455924, 27291650, 24360279
Identification Methods affinity chromatography technology, unspecified method, x-ray crystallography, two hybrid, nuclear magnetic resonance, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
GO:0045893 - positive regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1362
Hs

1 403
+ Hs
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+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
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+ Sp
+ Sp

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Last updated: 15 Jul 2024