HitPredict

Interactor 1: O62531 (O62531)
Adaptor protein complex 1, mu subunit (Clathrin-associated adaptor complex AP-1 medium chain) (Clathrin-associated protein) (LD31377p)
Gene: AP-1mu

Interactor 2: Q7KVR8 (Q7KVR8)
AP-1 complex subunit gamma
Gene: AP-1gamma

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22389401
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adap_comp_sub~Adaptin_N, Adaptin_N~Clat_adaptor_s
Common GO terms	GO:0006886 - intracellular protein transport GO:0030121 - AP-1 adaptor complex GO:0030136 - clathrin-coated vesicle GO:0033363 - secretory granule organization GO:0035615 - clathrin adaptor activity and 1 others more... GO:0048749 - compound eye development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 426 Dm			1 982
+	At
		187128 AP1M2_ARATH (2-424): 0: 526: 59.86		AP1G1_ARATH (39-973): 0: 688: 38.84
+	At
		1195473 AP1M1_ARATH (2-424): 3.29e-180: 510: 57.28		AP1G1_ARATH (39-973): 0: 688: 38.84
+	Hs
		925992 AP1M1_HUMAN (1-425): 0: 547: 82.63		AP2B1_HUMAN (71-955): 4.05e-173: 531: 13.69
+	Hs
		1014074 AP1M1_HUMAN (1-425): 0: 547: 82.63		AP1B1_HUMAN (71-955): 1.29e-169: 522: 14.44
+	Hs
		321614 AP2M1_HUMAN (5-424): 5.65e-164: 469: 40.73		AP2A1_HUMAN (37-954): 0: 587: 20.32
+	Hs
		926066 AP1M2_HUMAN (1-426): 0: 523: 75.18		AP2B1_HUMAN (71-955): 4.05e-173: 531: 13.69
+	Rn
		577193 AP2M1_RAT (5-424): 5.65e-164: 469: 40.73		AP2A2_RAT (37-954): 0: 581: 21.91
+	Hs
		1014107 AP1M2_HUMAN (1-426): 0: 523: 75.18		AP1B1_HUMAN (71-955): 1.29e-169: 522: 14.44
+	Hs
		302192 AP2M1_HUMAN (5-424): 5.65e-164: 469: 40.73		AP2A2_HUMAN (37-954): 0: 567: 21.60
+	Ce
		725358 AP1M_CAEEL (1-424): 0: 521: 75.71		Q9N4F3_CAEEL (71-937): 4.83e-160: 497: 16.67
+	At
		187886 AP2M_ARATH (1-424): 3.39e-171: 488: 42.83		APBLB_ARATH (71-857): 4.04e-165: 509: 16.33
+	At
		187823 AP2M_ARATH (1-424): 3.39e-171: 488: 42.83		AP2A1_ARATH (42-878): 1.18e-162: 505: 22.59
+	At
		187822 AP2M_ARATH (1-424): 3.39e-171: 488: 42.83		AP2A2_ARATH (42-878): 1.68e-161: 502: 22.59
+	At
		187750 AP2M_ARATH (1-424): 3.39e-171: 488: 42.83		APBLC_ARATH (71-857): 1.04e-159: 494: 16.60
+	Hs
		212662 AP1M1_HUMAN (1-425): 0: 547: 82.63		AP1G1_HUMAN (272-974): 8.95e-50: 192: 13.41
+	Mm
		612130 AP1M1_MOUSE (1-425): 0: 545: 81.93		AP1G1_MOUSE (272-974): 2.48e-50: 193: 13.67
+	Hs
		212676 AP1M2_HUMAN (1-426): 0: 523: 75.18		AP1G1_HUMAN (272-974): 8.95e-50: 192: 13.41
+	Hs
		276398 AP1M2_HUMAN (1-426): 0: 523: 75.18		AP1G2_HUMAN (238-972): 4.47e-34: 142: 14.46
+	Hs
		212655 AP2M1_HUMAN (5-424): 5.65e-164: 469: 40.73		AP1G1_HUMAN (272-974): 8.95e-50: 192: 13.41
+	Hs
		276382 AP2M1_HUMAN (5-424): 5.65e-164: 469: 40.73		AP1G2_HUMAN (238-972): 4.47e-34: 142: 14.46