HitPredict

Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: AP1B1 (Q10567)
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Gene: AP1B1

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	12419313
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 949
+	Hs
		251737 BUB1B_HUMAN (1-1050): 0: 827: 100.00		AP2B1_HUMAN (1-949): 0: 928: 83.04
+	Hs
		224108 BUB1_HUMAN (53-1042): 7.46e-170: 529: 19.04		AP1B1_HUMAN (1-949): 0: 971: 100.00
+	Hs
		126030 BUB1B_HUMAN (1-1050): 0: 827: 100.00		AP3B1_HUMAN (6-620): 0: 576: 27.99
+	Hs
		251831 BUB1B_HUMAN (1-1050): 0: 827: 100.00		AP4B1_HUMAN (15-629): 1.98e-153: 472: 29.21
+	Hs
		989172 AKT3_HUMAN (687-1044): 7.47e-112: 357: 14.02		AP2B1_HUMAN (1-949): 0: 928: 83.04
+	Dm
		51944 A1Z6I7_DROME (173-1026): 1.51e-84: 302: 15.32		Q24253_DROME (1-949): 0: 847: 72.74
+	Hs
		126027 BUB1_HUMAN (53-1042): 7.46e-170: 529: 19.04		AP3B1_HUMAN (6-620): 0: 576: 27.99
+	Dm
		1173123 Q9VMS5_DROME (45-450): 3.93e-49: 192: 21.36		Q24253_DROME (1-949): 0: 847: 72.74
+	Hs
		224184 BUB1_HUMAN (53-1042): 7.46e-170: 529: 19.04		AP4B1_HUMAN (15-629): 1.98e-153: 472: 29.21
+	Hs
		323712 KCC2D_HUMAN (764-1021): 3.16e-96: 316: 16.61		AP2A2_HUMAN (12-945): 0: 629: 18.33
+	Hs
		225779 AKT2_HUMAN (629-1044): 3.48e-113: 360: 12.59		AP1G1_HUMAN (12-822): 0: 559: 17.29