HitPredict

Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: AP4B1 (Q9Y6B7)
AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin)
Gene: AP4B1

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	12419313
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 739
+	Hs
		251737 BUB1B_HUMAN (1-1050): 0: 827: 100.00		AP2B1_HUMAN (3-611): 0: 562: 28.53
+	Hs
		251746 BUB1B_HUMAN (1-1050): 0: 827: 100.00		AP1B1_HUMAN (3-617): 0: 552: 28.57
+	Hs
		126030 BUB1B_HUMAN (1-1050): 0: 827: 100.00		AP3B1_HUMAN (3-612): 8.96e-143: 447: 21.09
+	Hs
		224184 BUB1_HUMAN (53-1042): 7.46e-170: 529: 19.04		AP4B1_HUMAN (1-739): 0: 656: 100.00
+	Hs
		224108 BUB1_HUMAN (53-1042): 7.46e-170: 529: 19.04		AP1B1_HUMAN (3-617): 0: 552: 28.57
+	Hs
		126027 BUB1_HUMAN (53-1042): 7.46e-170: 529: 19.04		AP3B1_HUMAN (3-612): 8.96e-143: 447: 21.09
+	Hs
		989172 AKT3_HUMAN (687-1044): 7.47e-112: 357: 14.02		AP2B1_HUMAN (3-611): 0: 562: 28.53
+	Dm
		51944 A1Z6I7_DROME (173-1026): 1.51e-84: 302: 15.32		Q24253_DROME (3-632): 0: 548: 27.54
+	Hs
		225779 AKT2_HUMAN (629-1044): 3.48e-113: 360: 12.59		AP1G1_HUMAN (6-601): 9.59e-154: 469: 14.02
+	Hs
		323712 KCC2D_HUMAN (764-1021): 3.16e-96: 316: 16.61		AP2A2_HUMAN (5-599): 1.68e-139: 435: 14.84
+	Dm
		1173123 Q9VMS5_DROME (45-450): 3.93e-49: 192: 21.36		Q24253_DROME (3-632): 0: 548: 27.54
+	Hs
		170456 AURKA_HUMAN (671-986): 1.26e-38: 151: 16.01		COPG1_HUMAN (31-522): 2.42e-75: 262: 17.00