HitPredict

Interactor 1: SRGP2 (O75044)
SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)
Gene: SRGAP2

Interactor 2: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29568061
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0046847 - filopodium assembly
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 586
+	Hs
		547031 ABR_HUMAN (25-664): 1.75e-80: 283: 16.52		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Hs
		506510 BCR_HUMAN (25-664): 1.36e-75: 274: 14.96		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Hs
		547091 RHG21_HUMAN (200-1027): 2.03e-71: 263: 13.52		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Hs
		547136 RHG24_HUMAN (357-975): 1.55e-72: 258: 16.81		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Hs
		506531 BCR_HUMAN (25-664): 1.36e-75: 274: 14.96		RADI_HUMAN (1-586): 7.83e-165: 484: 76.28
+	Hs
		719747 RHG24_HUMAN (357-975): 1.55e-72: 258: 16.81		RADI_HUMAN (1-586): 7.83e-165: 484: 76.28
+	Hs
		640115 RHG21_HUMAN (200-1027): 2.03e-71: 263: 13.52		MOES_HUMAN (1-586): 4.45e-161: 474: 72.70
+	Hs
		299236 CHIN_HUMAN (283-679): 4.75e-72: 249: 16.13		FARP2_HUMAN (2-548): 8.98e-114: 365: 19.42
+	Hs
		547235 RHG35_HUMAN (502-649): 2.56e-17: 90.1: 31.76		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Hs
		506517 BCR_HUMAN (25-664): 1.36e-75: 274: 14.96		PTN3_HUMAN (18-295): 2.55e-32: 134: 31.82