HitPredict

Interactor 1: ROCK2 (O75116)
Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)
Gene: ROCK2

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1388 Hs			1 783
+	Hs
		1035181 ROCK1_HUMAN (18-1383): 0: 667: 64.67		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		610741 KAPCB_HUMAN (66-395): 3.28e-127: 399: 36.23		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1071653 KS6A2_HUMAN (9-359): 8.39e-91: 312: 24.38		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172335 ST38L_HUMAN (74-417): 1.07e-79: 272: 40.47		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1069619 STK38_HUMAN (74-417): 6.46e-76: 261: 40.21		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1137875 MRCKA_HUMAN (685-1313): 1.42e-55: 215: 12.70		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172454 MRCKB_HUMAN (721-1313): 4.08e-46: 184: 12.17		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		148970 CTRO_HUMAN (329-921): 4.6e-23: 109: 12.00		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1069648 STK38_HUMAN (74-417): 6.46e-76: 261: 40.21		TRIM6_HUMAN (195-774): 1.16e-86: 284: 12.69
+	Hs
		1049033 STK38_HUMAN (74-417): 6.46e-76: 261: 40.21		TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80
+	Hs
		1071675 KS6A2_HUMAN (9-359): 8.39e-91: 312: 24.38		TRI11_HUMAN (1-121): 1.6e-09: 63.2: 20.66
+	Mm
		1143596 ST38L_MOUSE (74-417): 1.05e-80: 275: 40.73		TRI27_MOUSE (105-456): 7.29e-11: 67.4: 14.77
+	Hs
		537140 ST38L_HUMAN (74-417): 1.07e-79: 272: 40.47		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		1052661 STK38_HUMAN (74-417): 6.46e-76: 261: 40.21		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		537089 LATS2_HUMAN (64-390): 2.8e-66: 247: 36.90		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		149045 CTRO_HUMAN (329-921): 4.6e-23: 109: 12.00		CMYA5_HUMAN (262-606): 5.31e-36: 149: 19.32
+	Hs
		149258 CTRO_HUMAN (329-921): 4.6e-23: 109: 12.00		TRIM4_HUMAN (1-123): 1.51e-09: 63.2: 18.70