HitPredict

Interactor 1: KDM4A (O75164)
Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A)
Gene: KDM4A

Interactor 2: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	14527417, 16024779
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1064 Hs			1 2440
+	Hs
		261358 KDM4B_HUMAN (1-1064): 0: 1049: 49.95		NCOR1_HUMAN (1-2440): 0: 780: 100.00
+	Hs
		301148 KDM4B_HUMAN (1-1064): 0: 1049: 49.95		KMT2C_HUMAN (1352-2176): 4.42e-47: 190: 15.30
+	Hs
		261428 KDM5C_HUMAN (10-56): 7.71e-14: 78.5: 36.17		NCOR1_HUMAN (1-2440): 0: 780: 100.00
+	Hs
		261606 KDM5B_HUMAN (10-56): 2.48e-13: 76.9: 34.04		NCOR1_HUMAN (1-2440): 0: 780: 100.00
+	Hs
		319398 BRD1_HUMAN (484-925): 3.78e-79: 282: 19.65		NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71
+	Hs
		1355123 KDM5B_HUMAN (10-56): 2.48e-13: 76.9: 34.04		RCOR1_HUMAN (360-717): 6.64e-75: 260: 19.40