HitPredict

Interactor 1: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Interactor 2: MYB (P10242)
Transcriptional activator Myb (Proto-oncogene c-Myb)
Gene: MYB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.806

Property	Details
Experiments	14761981, 20195357
Identification Methods	pull down, affinity chromatography technology, display technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Myb_DNA-binding~Myb_DNA-binding
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2440 Hs			1 640
+	Hs
		261574 NCOR1_HUMAN (1-2440): 0: 780: 100.00		CDC5L_HUMAN (35-593): 4.73e-95: 311: 14.33
+	Hs
		486825 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		MYB_HUMAN (1-640): 0: 620: 100.00
+	Hs
		1303842 RCOR1_HUMAN (360-717): 6.64e-75: 260: 19.40		CDC5L_HUMAN (35-593): 4.73e-95: 311: 14.33
+	Hs
		724979 MYH9_HUMAN (302-1007): 2.78e-26: 121: 11.05		CDC5L_HUMAN (35-593): 4.73e-95: 311: 14.33
+	Hs
		1302921 MINT_HUMAN (468-2394): 3.2e-23: 111: 8.72		CDC5L_HUMAN (35-593): 4.73e-95: 311: 14.33
+	Hs
		1300907 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		CDC5L_HUMAN (35-593): 4.73e-95: 311: 14.33