HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0045292 - mRNA cis splicing, via spliceosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 156
+	Hs
		263864 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		PUF60_HUMAN (30-113): 1.88e-17: 80.1: 30.95
+	Hs
		263643 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		SF3B4_HUMAN (30-116): 8.18e-11: 60.8: 23.86
+	Sc
		987748 URN1_YEAST (186-646): 2.61e-58: 209: 12.87		HSH49_YEAST (37-113): 2.85e-25: 97.8: 37.18
+	Hs
		808914 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		CSTFT_HUMAN (31-148): 4.06e-35: 129: 24.37
+	Hs
		516402 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Hs
		154816 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49
+	Hs
		125268 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00
+	Hs
		154812 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		SF3B4_HUMAN (30-116): 8.18e-11: 60.8: 23.86
+	Hs
		269201 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Sc
		703283 PRP40_YEAST (144-667): 4.38e-18: 91.1: 16.90		NCBP2_YEAST (10-150): 3.97e-39: 132: 52.48
+	Hs
		269205 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		TIA1_HUMAN (1-140): 5.9e-21: 89.1: 19.58
+	Hs
		516643 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Hs
		125122 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Hs
		125430 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18
+	Hs
		1077493 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49
+	Hs
		269238 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		SF3B4_HUMAN (30-116): 8.18e-11: 60.8: 23.86
+	Hs
		125486 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49
+	Dm
		1250409 Q9VQK5_DROME (93-715): 2.58e-15: 82.7: 17.57		PUF68_DROME (40-141): 1.16e-17: 80.5: 31.43
+	Hs
		125479 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SF3B4_HUMAN (30-116): 8.18e-11: 60.8: 23.86