HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12577067
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 217
+	Hs
		516450 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		266891 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		522960 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Ce
		666211 Q17350_CAEEL (6-97): 3.68e-17: 82.5: 17.39		SEM5_CAEEL (3-69): 6.24e-14: 70: 28.36
+	Hs
		516342 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		523147 PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58