HitPredict

Interactor 1: WDR1 (O75083)
WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1)
Gene: WDR1

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25499913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 606 Hs			1 1298
+	Hs
		270386 WDR1_HUMAN (1-606): 3.89e-158: 468: 100.00		FBXW7_HUMAN (164-314): 4.21e-18: 92.2: 10.53
+	Hs
		964894 TBL3_HUMAN (241-604): 3.26e-44: 170: 12.76		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		845264 LIS1_HUMAN (356-605): 2.62e-38: 148: 15.07		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		965141 FBXW7_HUMAN (262-604): 2.82e-33: 137: 16.91		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		965276 NLE1_HUMAN (480-605): 9.64e-33: 133: 22.73		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		965071 WDR5B_HUMAN (7-131): 1.75e-21: 97.8: 17.05		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		964797 WDR5_HUMAN (524-605): 5.38e-17: 84.3: 25.30		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		1085692 TBL3_HUMAN (241-604): 3.26e-44: 170: 12.76		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Hs
		1387644 WDR3_HUMAN (407-606): 4.89e-30: 128: 21.57		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Hs
		845250 LIS1_HUMAN (356-605): 2.62e-38: 148: 15.07		LIS1_HUMAN (123-363): 2.02e-35: 142: 12.30
+	Mm
		988931 LIS1_MOUSE (356-605): 2e-38: 148: 15.07		LIS1_MOUSE (123-363): 1.82e-35: 142: 12.30
+	Hs
		965151 WDR5_HUMAN (524-605): 5.38e-17: 84.3: 25.30		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Dm
		1463899 WDS_DROME (394-605): 2.56e-48: 174: 11.11		WDS_DROME (174-342): 1.41e-22: 102: 10.53
+	Hs
		1334151 POC1B_HUMAN (12-85): 3.02e-18: 89.7: 20.00		POC1A_HUMAN (83-434): 1.48e-41: 160: 12.30
+	Hs
		845346 LIS1_HUMAN (356-605): 2.62e-38: 148: 15.07		KTNB1_HUMAN (167-610): 4.74e-17: 88.7: 8.64
+	At
		201145 AIP11_ARATH (158-605): 1.71e-38: 152: 14.38		GBLPA_ARATH (1-123): 2.81e-16: 83.7: 20.13
+	Hs
		1380064 FBXW7_HUMAN (262-604): 2.82e-33: 137: 16.91		FBXW7_HUMAN (164-314): 4.21e-18: 92.2: 10.53