HitPredict

Interactor 1: OFD1 (O75665)
Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein) (Protein 71-7A)
Gene: OFD1

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	34941261
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0015630 - microtubule cytoskeleton GO:0016020 - membrane GO:0036064 - ciliary basal body
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1012 Hs			1 480
+	Hs
		681696 MYH9_HUMAN (13-451): 1.62e-13: 77.4: 11.54		AKT1_HUMAN (1-480): 0: 586: 100.00
+	Hs
		551616 DESP_HUMAN (137-575): 8.46e-11: 68.8: 17.07		AKT1_HUMAN (1-480): 0: 586: 100.00
+	Hs
		682219 MYO5A_HUMAN (104-658): 3.36e-17: 89.7: 11.88		AKT2_HUMAN (1-477): 0: 559: 81.21
+	Hs
		681840 DCTN1_HUMAN (96-423): 6.49e-09: 62.3: 13.82		AKT1_HUMAN (1-480): 0: 586: 100.00
+	Hs
		610802 MYH4_HUMAN (29-982): 2.52e-32: 138: 10.84		KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86
+	Mm
		554927 MYH7_MOUSE (21-806): 2.81e-22: 106: 8.52		KPCE_MOUSE (53-474): 8.58e-146: 436: 39.53
+	Hs
		528359 MYH6_HUMAN (17-925): 4.1e-27: 121: 11.27		KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86
+	Mm
		554901 MYH6_MOUSE (65-579): 7.26e-16: 85.1: 9.48		KPCE_MOUSE (53-474): 8.58e-146: 436: 39.53
+	Hs
		610795 MYH2_HUMAN (15-748): 8.57e-20: 97.8: 10.71		KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86
+	Hs
		116964 MYH1_HUMAN (17-582): 6.6e-17: 88.6: 10.09		SGK1_HUMAN (104-478): 5.29e-146: 426: 44.97
+	Hs
		724784 MYH9_HUMAN (13-451): 1.62e-13: 77.4: 11.54		KPCE_HUMAN (53-474): 3.43e-146: 437: 39.77
+	Hs
		551672 DESP_HUMAN (137-575): 8.46e-11: 68.8: 17.07		KPCE_HUMAN (53-474): 3.43e-146: 437: 39.77
+	Hs
		522538 MYH1_HUMAN (17-582): 6.6e-17: 88.6: 10.09		KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86
+	Hs
		568568 MYH10_HUMAN (13-485): 7.3e-15: 82: 11.77		KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53
+	Hs
		568567 MYH9_HUMAN (13-451): 1.62e-13: 77.4: 11.54		KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53
+	Hs
		1071723 MRCKB_HUMAN (116-621): 1.91e-20: 100: 11.58		KS6A2_HUMAN (85-452): 6.82e-94: 301: 25.39