HitPredict

Interactor 1: OFD1 (O75665)
Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein) (Protein 71-7A)
Gene: OFD1

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	26638075, 24613305, 35709258
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0034451 - centriolar satellite GO:0060090 - molecular adaptor activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1012 Hs			1 703
+	Hs
		272545 OFD1_HUMAN (1-1012): 1.82e-122: 400: 100.00		DEUP1_HUMAN (8-523): 1.03e-62: 221: 28.30
+	Hs
		149184 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		528435 MYH4_HUMAN (29-982): 2.52e-32: 138: 10.84		MYH8_HUMAN (2-701): 1.11e-26: 119: 11.69
+	Hs
		528432 MYH13_HUMAN (3-735): 1.64e-21: 103: 11.60		MYH8_HUMAN (2-701): 1.11e-26: 119: 11.69
+	Hs
		725097 MYH11_HUMAN (19-734): 5.25e-22: 105: 9.38		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Hs
		502933 MYH4_HUMAN (29-982): 2.52e-32: 138: 10.84		MYH3_HUMAN (1-450): 1.24e-13: 76.9: 12.17
+	Rn
		361106 MYH6_RAT (17-925): 1.26e-26: 120: 12.04		MYH6_RAT (1-521): 9.79e-18: 90.4: 11.77
+	Hs
		148461 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Hs
		522657 MYH4_HUMAN (29-982): 2.52e-32: 138: 10.84		MYH7_HUMAN (367-695): 1.25e-09: 64: 10.00
+	Hs
		502901 MYH6_HUMAN (17-925): 4.1e-27: 121: 11.27		MYH3_HUMAN (1-450): 1.24e-13: 76.9: 12.17
+	Hs
		528356 MYH6_HUMAN (17-925): 4.1e-27: 121: 11.27		MYH6_HUMAN (300-700): 3.66e-13: 75.5: 11.47
+	Hs
		148466 MYH11_HUMAN (19-734): 5.25e-22: 105: 9.38		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		148460 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		725086 MYO5A_HUMAN (104-658): 3.36e-17: 89.7: 11.88		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1268126 MRCKB_HUMAN (116-621): 1.91e-20: 100: 11.58		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		148126 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		149126 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Rn
		222476 MRCKB_RAT (113-627): 1.46e-21: 103: 11.26		MRCKA_RAT (80-483): 2.52e-09: 62.9: 16.67
+	Rn
		222472 MRCKA_RAT (97-525): 2.81e-17: 89.7: 12.59		MRCKA_RAT (80-483): 2.52e-09: 62.9: 16.67