HitPredict

Interactor 1: KDM4A (O75164)
Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A)
Gene: KDM4A

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17555712
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1064 Hs			1 920
+	Mm
		618517 KDM4C_MOUSE (1-1064): 0: 1071: 51.86		ANDR_MOUSE (1-920): 0: 933: 84.30
+	Mm
		625750 KDM4A_MOUSE (1-1064): 0: 1127: 93.14		ESR1_MOUSE (378-904): 2.51e-129: 403: 21.30
+	Hs
		520129 KDM4D_HUMAN (7-504): 1.22e-174: 522: 47.36		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Mm
		625751 KDM4C_MOUSE (1-1064): 0: 1071: 51.86		ESR1_MOUSE (378-904): 2.51e-129: 403: 21.30
+	Hs
		322635 KDM4B_HUMAN (1-1064): 0: 1049: 49.95		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Mm
		625752 KDM4B_MOUSE (1-1064): 0: 1043: 49.72		ESR1_MOUSE (378-904): 2.51e-129: 403: 21.30
+	Hs
		322671 KDM4B_HUMAN (1-1064): 0: 1049: 49.95		ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51
+	Hs
		520350 KDM5D_HUMAN (10-56): 4.88e-14: 79.2: 34.04		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		520427 KDM5B_HUMAN (10-56): 2.49e-13: 76.9: 34.04		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		396648 JARD2_HUMAN (75-472): 9.39e-84: 298: 16.86		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Hs
		936666 BRPF1_HUMAN (432-926): 5.28e-85: 301: 18.70		ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51
+	Hs
		543599 BRPF3_HUMAN (728-893): 1.34e-64: 240: 32.58		ERR1_HUMAN (556-856): 1.29e-95: 309: 30.49
+	Hs
		395550 KDM5A_HUMAN (10-56): 1.13e-13: 78.1: 34.04		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Hs
		397146 KDM5B_HUMAN (10-56): 2.49e-13: 76.9: 34.04		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Hs
		403846 KDM5A_HUMAN (10-56): 1.13e-13: 78.1: 34.04		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85
+	Hs
		711836 KDM5A_HUMAN (10-56): 1.13e-13: 78.1: 34.04		ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51
+	Hs
		533236 KDM5B_HUMAN (10-56): 2.49e-13: 76.9: 34.04		RARB_HUMAN (458-902): 2.12e-111: 351: 17.98
+	Hs
		520518 KDM5A_HUMAN (10-56): 1.13e-13: 78.1: 34.04		RARA_HUMAN (460-902): 8.61e-110: 348: 19.87
+	Mm
		1190988 KDM5A_MOUSE (10-56): 9.52e-14: 78.5: 34.04		ERR2_MOUSE (467-904): 1.63e-109: 346: 23.64