Protein: JARD2
Protein Jumonji (Jumonji/ARID domain-containing protein 2)

Gene: JARD2, JARID2
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q92833

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0001889 - liver development
GO:0003677 - DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1369256

MTF2
Metal-response element-binding transcription factor 2

3

9

Small-scale

0.847

High

1155618

EZH2
Histone-lysine N-methyltransferase EZH2

12

18

Small-scale

0.761

High

1137432

SUZ12
Polycomb protein SUZ12

8

6

Small-scale

0.753

High

1252560

AEBP2
Zinc finger protein AEBP2

6

3

Small-scale

0.738

High

285395

EED
Polycomb protein EED

4

17

Small-scale

0.704

High

1368787

EZH1
Histone-lysine N-methyltransferase EZH1

4

18

Small-scale

0.704

High

1066427

RBBP4
Histone-binding protein RBBP4

3

13

Small-scale

0.675

High

1158950

RBBP7
Histone-binding protein RBBP7

2

13

Small-scale

0.628

High

851626

GATA4
Transcription factor GATA-4

2

13

Small-scale

0.624

High

210322

PHF1
PHD finger protein 1

1

9

High-throughput

0.618

High

1213574

PHF19
PHD finger protein 19

1

9

High-throughput

0.618

High

396648

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

916109

NKX25
Homeobox protein Nkx-2.5

1

20

Small-scale

0.561

High

1139785

SETB1
Histone-lysine N-methyltransferase SETDB1

1

15

Small-scale

0.561

High

674279

BRD2
Bromodomain-containing protein 2

1

18

High-throughput

0.536

High

1368025

HDAC2
Histone deacetylase 2

1

17

Small-scale

0.536

High

1369252

TBA1C
Tubulin alpha-1C chain

1

4

High-throughput

0.536

High

390128

ALBU
Albumin

1

0

High-throughput

0.513

High

912096

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.513

High

876099

TCPE
T-complex protein 1 subunit epsilon

1

10

High-throughput

0.489

High

65639

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

1

3

High-throughput

0.479

High

946846

H2B1D
Histone H2B type 1-D

1

12

High-throughput

0.479

High

1033738

PO5F1
POU domain, class 5, transcription factor 1

1

11

High-throughput

0.479

High

1095285

REST
RE1-silencing transcription factor

1

1

High-throughput

0.479

High

1308468

VRK3
Serine/threonine-protein kinase VRK3

1

1

High-throughput

0.479

High

1363071

DDB2
DNA damage-binding protein 2

1

11

Small-scale

0.479

High

1369250

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

2

Small-scale

0.479

High

1369251

H2B1L
Histone H2B type 1-L

1

11

High-throughput

0.479

High

1369253

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

2

Small-scale

0.479

High

1369254

NANOG
Homeobox protein NANOG

1

20

High-throughput

0.479

High

1015271

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.458

High

1107073

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1369249

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.458

High

1115335

CUL4B
Cullin-4B

1

11

Small-scale

0.445

High

1157843

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.445

High

1030753

CAP1
Adenylyl cyclase-associated protein 1

1

1

High-throughput

0.437

High

1369255

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.279

Low

1152180

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025