HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: UBP48 (Q86UV5)
Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48)
Gene: USP48

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28242625, 33903120
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 1035
+	Hs
		591716 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		UBP48_HUMAN (1-1035): 0: 1278: 100.00
+	Hs
		419058 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP48_HUMAN (1-1035): 0: 1278: 100.00
+	Hs
		1162818 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP48_HUMAN (1-1035): 0: 1278: 100.00
+	Mm
		1191124 H2A1H_MOUSE (1-125): 1.15e-64: 203: 62.50		UBP48_MOUSE (1-1035): 0: 1248: 92.13
+	Hs
		277839 H2AY_HUMAN (1-369): 6.52e-165: 467: 100.00		UBP36_HUMAN (2-506): 3.16e-99: 340: 18.32
+	Hs
		1453887 H2AW_HUMAN (1-368): 1.42e-145: 418: 66.04		UBP36_HUMAN (2-506): 3.16e-99: 340: 18.32
+	Hs
		591694 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		U17L2_HUMAN (14-532): 2.06e-115: 368: 20.37
+	Hs
		591767 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		UBP7_HUMAN (66-487): 3.37e-99: 339: 26.05
+	Hs
		419247 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP36_HUMAN (2-506): 3.16e-99: 340: 18.32
+	Hs
		419122 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP7_HUMAN (66-487): 3.37e-99: 339: 26.05
+	Hs
		1162856 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP7_HUMAN (66-487): 3.37e-99: 339: 26.05
+	Hs
		1413569 H2AJ_HUMAN (1-125): 1.22e-63: 200: 62.50		UBP36_HUMAN (2-506): 3.16e-99: 340: 18.32
+	Hs
		288334 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP2_HUMAN (1-425): 6.68e-100: 329: 20.00
+	Hs
		288424 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP2_HUMAN (1-425): 6.68e-100: 329: 20.00
+	Hs
		275894 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP12_HUMAN (79-422): 9.73e-101: 323: 22.58
+	Hs
		419295 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP3_HUMAN (13-404): 6.83e-98: 321: 19.87
+	Hs
		967150 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP46_HUMAN (88-422): 2.68e-100: 321: 23.42
+	Hs
		419275 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP22_HUMAN (55-400): 9.75e-94: 309: 20.84
+	Hs
		1162926 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP22_HUMAN (55-400): 9.75e-94: 309: 20.84
+	Hs
		1162930 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP20_HUMAN (18-199): 1.13e-27: 123: 17.77