HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: UBP36 (Q9P275)
Ubiquitin carboxyl-terminal hydrolase 36 (EC 2.3.2.-) (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36)
Gene: USP36

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36912080
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 1123
+	Hs
		1453887 H2AW_HUMAN (1-368): 1.42e-145: 418: 66.04		UBP36_HUMAN (1-1123): 0: 666: 100.00
+	Hs
		419247 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP36_HUMAN (1-1123): 0: 666: 100.00
+	Hs
		1413569 H2AJ_HUMAN (1-125): 1.22e-63: 200: 62.50		UBP36_HUMAN (1-1123): 0: 666: 100.00
+	Hs
		277729 H2AY_HUMAN (1-369): 6.52e-165: 467: 100.00		UBP48_HUMAN (115-935): 1.8e-98: 338: 14.10
+	Hs
		591694 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		U17L2_HUMAN (58-578): 1.01e-123: 391: 36.47
+	Hs
		419275 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP22_HUMAN (109-428): 2.54e-111: 358: 25.55
+	Hs
		1162926 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP22_HUMAN (109-428): 2.54e-111: 358: 25.55
+	Mm
		1191124 H2A1H_MOUSE (1-125): 1.15e-64: 203: 62.50		UBP48_MOUSE (115-935): 4.2e-100: 342: 14.55
+	Hs
		419043 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP51_HUMAN (117-423): 6.49e-103: 342: 24.57
+	Hs
		591716 H2AX_HUMAN (1-142): 1.08e-65: 206: 60.69		UBP48_HUMAN (115-935): 1.8e-98: 338: 14.10
+	Hs
		967150 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP46_HUMAN (104-424): 1.23e-107: 343: 24.58
+	Hs
		1162809 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP51_HUMAN (117-423): 6.49e-103: 342: 24.57
+	Hs
		275894 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP12_HUMAN (82-424): 2.52e-107: 342: 23.94
+	Hs
		419058 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP48_HUMAN (115-935): 1.8e-98: 338: 14.10
+	Hs
		1162818 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP48_HUMAN (115-935): 1.8e-98: 338: 14.10
+	Hs
		288334 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP2_HUMAN (8-428): 3.41e-97: 323: 26.14
+	Hs
		288424 H2A2C_HUMAN (1-125): 9.27e-64: 201: 63.28		UBP2_HUMAN (8-428): 3.41e-97: 323: 26.14
+	Hs
		419295 H2A1B_HUMAN (1-126): 1.28e-64: 203: 62.02		UBP3_HUMAN (101-424): 2.97e-94: 312: 27.59
+	Sc
		419805 H2A2_YEAST (14-123): 1.55e-41: 144: 67.27		UBP8_YEAST (61-424): 8.65e-99: 323: 26.19