HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WW~WW
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 400
+	Hs
		163829 TCRG1_HUMAN (6-820): 3.21e-41: 166: 16.26		WWTR1_HUMAN (1-400): 5.18e-126: 371: 100.00
+	Hs
		862433 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		WWTR1_HUMAN (1-400): 5.18e-126: 371: 100.00
+	Mm
		862609 YAP1_MOUSE (34-410): 1.35e-40: 158: 11.81		WWTR1_MOUSE (1-400): 7.57e-120: 355: 91.00
+	Hs
		163723 TCRG1_HUMAN (6-820): 3.21e-41: 166: 16.26		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		131812 WWP2_HUMAN (2-352): 2.92e-41: 165: 16.30		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		861908 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		280850 PR40A_HUMAN (1-957): 3.8e-106: 353: 100.00		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Ce
		1376997 Q95PX7_CAEEL (23-819): 4.39e-62: 229: 17.40		WWP1_CAEEL (8-225): 4.45e-50: 182: 13.96
+	Hs
		132289 WWP2_HUMAN (2-352): 2.92e-41: 165: 16.30		WWP1_HUMAN (3-386): 5.13e-64: 222: 13.86
+	Hs
		862443 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		WWP1_HUMAN (3-386): 5.13e-64: 222: 13.86
+	Hs
		132236 WWP2_HUMAN (2-352): 2.92e-41: 165: 16.30		ITCH_HUMAN (37-356): 2.66e-60: 211: 14.83
+	Hs
		131562 WWP2_HUMAN (2-352): 2.92e-41: 165: 16.30		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46
+	Hs
		862377 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		ITCH_HUMAN (37-356): 2.66e-60: 211: 14.83
+	Hs
		862247 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		HECW1_HUMAN (14-327): 1.33e-53: 193: 14.29
+	Hs
		862283 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		KIBRA_HUMAN (123-265): 3.1e-45: 169: 18.88
+	Hs
		862216 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		WWC2_HUMAN (121-264): 2.85e-43: 163: 15.97
+	Hs
		861512 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		NEDD4_HUMAN (109-352): 7.43e-23: 103: 11.00
+	Hs
		163840 TCRG1_HUMAN (6-820): 3.21e-41: 166: 16.26		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		862390 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		NED4L_HUMAN (164-352): 3.04e-13: 73.5: 13.20