HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: WDR75 (Q8IWA0)
WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog)
Gene: WDR75

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	23891004
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 830
+	Hs
		282871 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		WDR5_HUMAN (477-696): 2.27e-34: 136: 15.25
+	Hs
		282843 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		LIS1_HUMAN (475-709): 2.67e-32: 131: 10.92
+	Hs
		1309163 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		TBL1Y_HUMAN (324-669): 3.68e-52: 192: 11.11
+	Hs
		1240442 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		POC1A_HUMAN (1-181): 2.15e-35: 141: 17.39
+	Hs
		245633 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		TBL1X_HUMAN (396-696): 3.68e-30: 128: 13.74
+	Hs
		903174 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		TBL3_HUMAN (1-491): 1e-71: 253: 11.49
+	Dm
		1358845 WDS_DROME (137-339): 1.46e-47: 165: 20.69		WDS_DROME (437-660): 3.66e-42: 159: 13.60
+	Hs
		903418 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		WDR5_HUMAN (477-696): 2.27e-34: 136: 15.25
+	Hs
		254111 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		WDR1_HUMAN (435-740): 2.78e-22: 104: 9.18
+	Hs
		863508 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		COPA_HUMAN (5-364): 2.65e-16: 86: 12.59
+	Hs
		903551 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		WDR5_HUMAN (477-696): 2.27e-34: 136: 15.25
+	Hs
		878165 SEC13_HUMAN (28-281): 8.06e-19: 87.4: 29.64		WDR5_HUMAN (477-696): 2.27e-34: 136: 15.25
+	Hs
		903077 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		WDR5_HUMAN (477-696): 2.27e-34: 136: 15.25
+	Sp
		999842 TUP11_SCHPO (175-339): 1.79e-29: 120: 15.76		TUP12_SCHPO (473-676): 4.26e-20: 97.2: 12.74
+	Hs
		792949 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		LIS1_HUMAN (475-709): 2.67e-32: 131: 10.92
+	Sp
		999838 TUP11_SCHPO (175-339): 1.79e-29: 120: 15.76		TUP11_SCHPO (497-707): 2.34e-18: 91.8: 12.73
+	Ca
		483033 TUP1_CANAL (180-338): 4.8e-28: 115: 18.87		TUP1_CANAL (436-617): 7.61e-12: 70.8: 19.05
+	Hs
		1346954 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		NLE1_HUMAN (530-700): 1.91e-18: 91.2: 8.94
+	Hs
		903349 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		WDR5B_HUMAN (13-230): 5.24e-19: 91.2: 18.10
+	Hs
		863397 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		COPA_HUMAN (5-364): 2.65e-16: 86: 12.59