Protein: NR1H4
Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14)

Gene: NR1H4
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q96RI1

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704549

RXRB
Retinoic acid receptor RXR-beta

5

20

High-throughput

0.929

High

1153785

NCOA1
Nuclear receptor coactivator 1

5

20

Small-scale

0.922

High

873168

RXRG
Retinoic acid receptor RXR-gamma

3

20

High-throughput

0.845

High

625840

RXRA
Retinoic acid receptor RXR-alpha

2

20

Small-scale

0.821

High

396757

ESR1
Estrogen receptor

2

19

Small-scale

0.776

High

558346

XRCC6
X-ray repair cross-complementing protein 6

1

15

Small-scale

0.586

High

559462

XRCC5
X-ray repair cross-complementing protein 5

1

15

Small-scale

0.586

High

1008294

PRKDC
DNA-dependent protein kinase catalytic subunit

1

12

Small-scale

0.586

High

1355987

SETD7
Histone-lysine N-methyltransferase SETD7

1

5

Small-scale

0.562

High

1401346

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

20

Small-scale

0.561

High

1388698

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

20

Small-scale

0.536

High

1392033

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

20

Small-scale

0.527

High

272843

PHF2
Lysine-specific demethylase PHF2

1

20

Small-scale

0.516

High

998708

H31
Histone H3.1

1

5

Small-scale

0.501

High

1067620

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.501

High

1130591

NCOA6
Nuclear receptor coactivator 6

1

20

Small-scale

0.501

High

1132416

CASP8
Caspase-8

1

5

Small-scale

0.501

High

1247672

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

20

Small-scale

0.501

High

1401348

NCOR2
Nuclear receptor corepressor 2

1

20

Small-scale

0.501

High

409043

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.481

High

1051682

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

3

Small-scale

0.481

High

138280

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

8

High-throughput

0.479

High

278407

NCOR1
Nuclear receptor corepressor 1

1

20

Small-scale

0.479

High

987877

GRB2
Growth factor receptor-bound protein 2

1

16

High-throughput

0.479

High

991403

SUMO1
Small ubiquitin-related modifier 1

1

11

Small-scale

0.479

High

1045666

TF65
Transcription factor p65

1

20

Small-scale

0.479

High

1051292

KPCZ
Protein kinase C zeta type

1

17

Small-scale

0.479

High

1085460

SRBP2
Sterol regulatory element-binding protein 2

1

20

Small-scale

0.479

High

1098587

GPS2
G protein pathway suppressor 2

1

4

Small-scale

0.479

High

1293402

CARM1
Histone-arginine methyltransferase CARM1

1

20

Small-scale

0.479

High

1401343

ANM1
Protein arginine N-methyltransferase 1

1

20

Small-scale

0.479

High

1401344

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

2

Small-scale

0.479

High

1401345

MLXPL
Carbohydrate-responsive element-binding protein

1

20

Small-scale

0.479

High

1401347

HDAC6
Protein deacetylase HDAC6

1

20

Small-scale

0.479

High

725800

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

Small-scale

0.458

High

1133273

ARI5B
AT-rich interactive domain-containing protein 5B

1

20

Small-scale

0.445

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025