HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: T22D1 (Q15714)
TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)
Gene: TSC22D1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 1073
+	Mm
		1222463 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		HCFC1_MOUSE (2-1061): 2.72e-12: 73.5: 9.48
+	Mm
		59411 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		CHD7_MOUSE (487-985): 4.48e-12: 73.1: 11.19
+	Hs
		285152 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		HCFC1_HUMAN (1-1073): 4.55e-12: 72.7: 9.29
+	Mm
		1239998 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		IF4G1_MOUSE (516-1073): 7.89e-11: 68.7: 12.37
+	Hs
		285071 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		SON_HUMAN (486-849): 3.8e-10: 66.5: 16.71
+	Hs
		285279 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		MDC1_HUMAN (585-1069): 1.09e-09: 65: 13.27
+	Mm
		92778 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		D3Z656_MOUSE (87-514): 1.14e-09: 65: 9.91
+	Hs
		261458 TBL1X_HUMAN (25-441): 2.18e-71: 237: 11.74		T22D4_HUMAN (817-1056): 3.62e-23: 105: 34.15
+	Hs
		1420011 TBL1R_HUMAN (25-267): 1.29e-47: 172: 14.40		T22D4_HUMAN (817-1056): 3.62e-23: 105: 34.15
+	Hs
		1380165 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		PRR36_HUMAN (2-918): 2.36e-26: 119: 9.38
+	Hs
		1380281 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		T22D4_HUMAN (817-1056): 3.62e-23: 105: 34.15
+	Dm
		52083 TAF5_DROME (85-367): 9.58e-17: 84.8: 17.48		A1Z6M0_DROME (192-991): 3.54e-21: 102: 14.55
+	Dm
		1481151 FBXW7_DROME (224-441): 2.91e-25: 111: 15.53		Q9VLS7_DROME (1-689): 9.49e-10: 65.4: 9.86
+	Hs
		1130588 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		NCOA6_HUMAN (258-1070): 4.07e-09: 63.1: 10.75
+	Hs
		615449 NLE1_HUMAN (296-440): 9.08e-25: 108: 16.45		SON_HUMAN (486-849): 3.8e-10: 66.5: 16.71
+	Hs
		1235072 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		ADNP2_HUMAN (615-963): 2.56e-12: 73.5: 17.18
+	Hs
		615433 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		SON_HUMAN (486-849): 3.8e-10: 66.5: 16.71
+	Hs
		1338750 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		ARI1B_HUMAN (69-1065): 4.84e-10: 66.2: 9.40
+	Hs
		1129693 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		MDC1_HUMAN (585-1069): 1.09e-09: 65: 13.27
+	Mm
		965395 WDR5_MOUSE (335-440): 3.34e-14: 75.4: 15.09		KMT2C_MOUSE (2-789): 4.01e-15: 83.1: 8.99