HitPredict

Interactor 1: PIF3 (O80536)
Transcription factor PIF3 (Basic helix-loop-helix protein 8) (AtbHLH8) (bHLH 8) (Phytochrome-associated protein 3) (Phytochrome-interacting factor 3) (Transcription factor EN 100) (bHLH transcription factor bHLH008)
Gene: PIF3

Interactor 2: PIF5 (Q84LH8)
Transcription factor PIF5 (Basic helix-loop-helix protein 65) (AtbHLH65) (bHLH 65) (Phytochrome interacting factor-like 6) (Phytochrome-interacting factor 5) (Transcription factor EN 103) (bHLH transcription factor bHLH065)
Gene: PIF5

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	15356333
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0009409 - response to cold GO:0009585 - red, far-red light phototransduction and 1 others more... GO:0046983 - protein dimerization activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 524 At			1 444
+	At
		285447 PIF3_ARATH (1-524): 4.1e-105: 326: 100.00		PIF1_ARATH (6-434): 2.83e-41: 154: 25.00
+	At
		285451 PIF3_ARATH (1-524): 4.1e-105: 326: 100.00		PIF4_ARATH (8-437): 2.49e-40: 151: 49.35
+	At
		285433 PIF3_ARATH (1-524): 4.1e-105: 326: 100.00		PIF3_ARATH (62-395): 9.61e-36: 140: 24.26
+	At
		285455 PIF3_ARATH (1-524): 4.1e-105: 326: 100.00		HFR1_ARATH (207-384): 2.83e-31: 123: 20.21
+	At
		1195586 PIF1_ARATH (90-500): 7.04e-36: 141: 21.90		PIF5_ARATH (1-444): 2.71e-86: 272: 100.00
+	At
		222004 MYC4_ARATH (27-461): 2.75e-58: 205: 13.81		MYC4_ARATH (36-357): 3.02e-33: 133: 13.81
+	At
		222019 MYC4_ARATH (27-461): 2.75e-58: 205: 13.81		MYC3_ARATH (49-358): 5.65e-33: 133: 16.61
+	At
		1107239 MYC2_ARATH (21-447): 1.73e-50: 184: 14.78		MYC3_ARATH (49-358): 5.65e-33: 133: 16.61
+	At
		222008 MYC2_ARATH (21-447): 1.73e-50: 184: 14.78		MYC4_ARATH (36-357): 3.02e-33: 133: 13.81
+	At
		1323537 MYC3_ARATH (27-416): 9.93e-48: 176: 13.76		MYC3_ARATH (49-358): 5.65e-33: 133: 16.61
+	At
		1210191 PIF1_ARATH (90-500): 7.04e-36: 141: 21.90		PIF1_ARATH (6-434): 2.83e-41: 154: 25.00
+	At
		1123026 PIF1_ARATH (90-500): 7.04e-36: 141: 21.90		PIF7_ARATH (129-343): 5.76e-41: 151: 32.41
+	At
		1209825 BH076_ARATH (233-459): 1.77e-36: 141: 25.00		BH063_ARATH (66-399): 6.46e-40: 147: 16.37
+	At
		1108196 BH060_ARATH (149-510): 1.35e-38: 148: 16.15		HBI1_ARATH (126-396): 4.89e-32: 126: 16.61
+	At
		1108183 BH060_ARATH (149-510): 1.35e-38: 148: 16.15		BEE2_ARATH (152-397): 4.46e-31: 123: 19.60
+	At
		1108189 BH060_ARATH (149-510): 1.35e-38: 148: 16.15		BH079_ARATH (109-368): 2.15e-31: 123: 18.45
+	At
		188529 BH003_ARATH (186-476): 5.03e-36: 141: 14.43		BH084_ARATH (76-330): 6.92e-32: 125: 17.88
+	At
		188530 BH003_ARATH (186-476): 5.03e-36: 141: 14.43		RSL2_ARATH (38-335): 9.53e-31: 123: 16.05