HitPredict

Interactor 1: RSZ22 (O81126)
Serine/arginine-rich splicing factor RSZ22 (RS-containing zinc finger protein 22) (At-RSZ22) (At-RSZp22) (AtRSZ22)
Gene: RSZ22

Interactor 2: RU17 (Q42404)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: RNU1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	9761791, 10593939
Identification Methods	two hybrid, pull down, far western blotting
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~U1snRNP70_N
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003729 - mRNA binding GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 At			1 427
+	At
		1257894 RZ22A_ARATH (1-200): 3.17e-28: 106: 74.63		U1135_ARATH (123-406): 1.98e-62: 206: 29.55
+	At
		286440 RSZ21_ARATH (1-176): 4.09e-25: 98.4: 61.36		U1135_ARATH (123-406): 1.98e-62: 206: 29.55
+	At
		1257896 SR30_ARATH (3-81): 1.2e-22: 93.8: 41.98		U1135_ARATH (123-406): 1.98e-62: 206: 29.55
+	At
		1257878 RSZ33_ARATH (2-191): 6.09e-20: 86.8: 28.16		U1135_ARATH (123-406): 1.98e-62: 206: 29.55
+	At
		286435 RSZ21_ARATH (1-176): 4.09e-25: 98.4: 61.36		RU17_ARATH (1-427): 9.46e-50: 176: 100.00
+	At
		1114811 SR30_ARATH (3-81): 1.2e-22: 93.8: 41.98		RU17_ARATH (1-427): 9.46e-50: 176: 100.00
+	Hs
		1083184 ZCRB1_HUMAN (2-122): 1.76e-27: 105: 28.57		U1SBP_HUMAN (118-336): 2.39e-46: 161: 37.90
+	Hs
		442193 SRSF7_HUMAN (2-114): 8.71e-28: 106: 46.02		RU17_HUMAN (42-259): 6.88e-36: 138: 51.12
+	Hs
		442329 ZCRB1_HUMAN (2-122): 1.76e-27: 105: 28.57		RU17_HUMAN (42-259): 6.88e-36: 138: 51.12
+	Ce
		999480 RSP6_CAEEL (2-77): 5.34e-21: 87.2: 50.00		Q09584_CAEEL (42-290): 2.1e-37: 140: 40.39
+	Hs
		442068 SRSF3_HUMAN (3-90): 6.86e-21: 86.4: 45.46		RU17_HUMAN (42-259): 6.88e-36: 138: 51.12
+	Hs
		516466 SRSF3_HUMAN (3-90): 6.86e-21: 86.4: 45.46		PABP1_HUMAN (129-381): 2.9e-33: 133: 14.34
+	Hs
		680437 SRSF3_HUMAN (3-90): 6.86e-21: 86.4: 45.46		TIA1_HUMAN (133-317): 7.24e-29: 118: 16.33
+	Hs
		474017 SRSF3_HUMAN (3-90): 6.86e-21: 86.4: 45.46		PAB4L_HUMAN (139-370): 1.79e-28: 116: 14.35
+	At
		286436 RSZ21_ARATH (1-176): 4.09e-25: 98.4: 61.36		CYP59_ARATH (66-371): 4.78e-22: 100: 18.89
+	At
		1163070 SR30_ARATH (3-81): 1.2e-22: 93.8: 41.98		CYP59_ARATH (66-371): 4.78e-22: 100: 18.89
+	At
		1163064 RSZ33_ARATH (2-191): 6.09e-20: 86.8: 28.16		CYP59_ARATH (66-371): 4.78e-22: 100: 18.89
+	Hs
		1252789 ZCRB1_HUMAN (2-122): 1.76e-27: 105: 28.57		RBM19_HUMAN (84-220): 2.34e-14: 77.2: 22.86
+	Hs
		951962 SRSF3_HUMAN (3-90): 6.86e-21: 86.4: 45.46		CIRBP_HUMAN (140-302): 2.39e-17: 81.1: 22.70
+	Hs
		952192 SRSF3_HUMAN (3-90): 6.86e-21: 86.4: 45.46		RBM19_HUMAN (84-220): 2.34e-14: 77.2: 22.86