HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.700

Property	Details
Experiments	25416956, 32296183, 23105109, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 605 Hs			1 513
+	Hs
		288349 UBP2_HUMAN (1-605): 0: 634: 100.00		RO52_HUMAN (1-500): 1.78e-154: 450: 36.78
+	Hs
		288516 UBP2_HUMAN (1-605): 0: 634: 100.00		TRI39_HUMAN (7-494): 1.35e-150: 442: 37.20
+	Hs
		288510 UBP2_HUMAN (1-605): 0: 634: 100.00		TRIM5_HUMAN (1-494): 1.63e-123: 372: 28.65
+	Hs
		288457 UBP2_HUMAN (1-605): 0: 634: 100.00		TRI50_HUMAN (1-487): 2.72e-118: 358: 27.70
+	Hs
		288505 UBP2_HUMAN (1-605): 0: 634: 100.00		TRI34_HUMAN (1-494): 9.15e-106: 326: 30.31
+	Hs
		288543 UBP2_HUMAN (1-605): 0: 634: 100.00		TRI35_HUMAN (3-492): 2.78e-102: 317: 26.45
+	Hs
		1420577 UBP21_HUMAN (72-604): 1.37e-127: 388: 35.15		TRIM5_HUMAN (1-494): 1.63e-123: 372: 28.65
+	Hs
		1131102 UBP10_HUMAN (62-600): 2.12e-101: 327: 19.70		TRI11_HUMAN (1-500): 1.01e-141: 418: 38.20
+	Hs
		571904 UBP11_HUMAN (453-605): 5.35e-29: 124: 37.98		TRI27_HUMAN (1-513): 2.46e-175: 505: 100.00
+	Hs
		572296 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		TRI27_HUMAN (1-513): 2.46e-175: 505: 100.00
+	Hs
		623608 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		RO52_HUMAN (1-500): 1.78e-154: 450: 36.78
+	Hs
		623313 UBP4_HUMAN (447-597): 2.23e-28: 122: 42.76		RO52_HUMAN (1-500): 1.78e-154: 450: 36.78
+	Hs
		322904 UBP19_HUMAN (454-602): 3.29e-23: 107: 39.62		RO52_HUMAN (1-500): 1.78e-154: 450: 36.78
+	Hs
		1390324 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		TRI11_HUMAN (1-500): 1.01e-141: 418: 38.20
+	Hs
		1420581 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		TRIM5_HUMAN (1-494): 1.63e-123: 372: 28.65
+	Hs
		1491399 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		TRI17_HUMAN (1-482): 1.87e-118: 358: 35.02
+	Hs
		1089276 UBP36_HUMAN (162-598): 1.94e-101: 334: 26.70		TRI26_HUMAN (385-482): 2.77e-09: 61.6: 40.40