HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.911

Property	Details
Experiments	25416956, 29892012, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 513
+	Hs
		1368310 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		ASAP1_HUMAN (65-510): 3.94e-43: 166: 14.44
+	Hs
		169771 HGS_HUMAN (135-518): 5.13e-16: 83.2: 10.95		ABI2_HUMAN (1-513): 2.17e-91: 290: 100.00
+	Hs
		1117357 SPTN1_HUMAN (103-481): 1.46e-55: 203: 14.59		SRC8_HUMAN (271-507): 3.77e-33: 134: 17.84
+	Hs
		290242 TM1L1_HUMAN (6-494): 1.97e-65: 221: 15.62		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Rn
		204806 SPTN1_RAT (103-481): 1.05e-55: 204: 14.35		SRBS2_RAT (293-509): 7.66e-17: 85.9: 14.35
+	Hs
		987621 SPTN1_HUMAN (103-481): 1.46e-55: 203: 14.59		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		1117374 SPTN1_HUMAN (103-481): 1.46e-55: 203: 14.59		ITSN1_HUMAN (424-510): 4.45e-11: 67.9: 21.28
+	Hs
		1154182 ITSN1_HUMAN (188-414): 1.92e-46: 176: 22.50		ITSN2_HUMAN (425-512): 2.11e-13: 75.2: 29.55
+	Hs
		1154087 ITSN1_HUMAN (188-414): 1.92e-46: 176: 22.50		ITSN1_HUMAN (424-510): 4.45e-11: 67.9: 21.28
+	Hs
		215925 ITSN1_HUMAN (188-414): 1.92e-46: 176: 22.50		SYNJ1_HUMAN (83-381): 1.45e-09: 62.9: 12.42
+	Hs
		292881 GRAP2_HUMAN (175-256): 5.1e-13: 72: 41.46		ASAP1_HUMAN (65-510): 3.94e-43: 166: 14.44
+	Hs
		584510 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		VAV_HUMAN (276-513): 7.12e-31: 129: 17.06
+	Hs
		571667 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		HCLS1_HUMAN (271-508): 6.97e-30: 124: 19.86
+	Mm
		699355 GRB2_MOUSE (207-262): 4.6e-12: 67.4: 52.63		VAV_MOUSE (299-513): 3.12e-27: 117: 19.30
+	Hs
		169499 HGS_HUMAN (135-518): 5.13e-16: 83.2: 10.95		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		987629 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		ARHG7_HUMAN (451-508): 2.17e-18: 90.8: 41.38
+	Hs
		72966 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		B1ALK7_HUMAN (451-508): 3.78e-18: 89.7: 41.38
+	Hs
		292823 GRAP2_HUMAN (175-256): 5.1e-13: 72: 41.46		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		987513 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		215914 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		SYNJ1_HUMAN (83-381): 1.45e-09: 62.9: 12.42