Interactor 1: SLIT2 (O94813)
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]
Gene: SLIT2

Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, EGF~EGF_CA
Common GO terms GO:0003184 - pulmonary valve morphogenesis
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0007411 - axon guidance
GO:0016020 - membrane
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1529
Hs

1 2471
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Last updated: 15 Jul 2024