HitPredict

Interactor 1: TOX4 (O94842)
TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
Gene: TOX4

Interactor 2: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.687

Property	Details
Experiments	28330616, 30344098, 20516061, 24366813
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0072357 - PTW/PP1 phosphatase complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 323
+	Hs
		297480 TOX4_HUMAN (1-621): 4.57e-110: 345: 100.00		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		297481 TOX4_HUMAN (1-621): 4.57e-110: 345: 100.00		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		737768 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		905854 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		906428 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		617274 SP100_HUMAN (164-303): 3.95e-21: 100: 24.83		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		915171 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73
+	Dm
		113980 M9PB30_DROME (22-604): 8.37e-09: 61: 11.35		PP1B_DROME (1-323): 0: 552: 82.48