HitPredict

Interactor 1: TRIO (O75962)
Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein)
Gene: TRIO

Interactor 2: TRIO (O75962)
Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein)
Gene: TRIO

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 21422296
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CRAL_TRIO_2~CRAL_TRIO_2, I-set~I-set, I-set~Pkinase, Pkinase~Pkinase, RhoGEF~RhoGEF, RhoGEF~SH3_1, RhoGEF~SOS1_NGEF_PH, SH3_1~SH3_1, SH3_1~SOS1_NGEF_PH, SOS1_NGEF_PH~SOS1_NGEF_PH, Spectrin~Spectrin
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 12 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 3097
Hs

1 3097
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+ Ce
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Service provided by Combinatics, Japan

Last updated: 11Aug2025