Interactor 1: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 38334954
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~EF-hand_7, CH~EFhand_Ca_insen, CH~Spectrin, EF-hand_7~EF-hand_7, EF-hand_7~EFhand_Ca_insen, EF-hand_7~Spectrin, EF-hand_7~GAS2, SH3_10~Spectrin, EFhand_Ca_insen~Spectrin, Spectrin~Spectrin, Spectrin~Spectrin_3
Common GO terms GO:0003779 - actin binding
GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0015630 - microtubule cytoskeleton
GO:0016020 - membrane
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 7570
Hs

1 2472
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Last updated: 11Aug2025