HitPredict

Interactor 1: A4PIW0 (A4PIW0)
Fusion protein SYT-SSX2
Gene: SYT-SSX2

Interactor 2: SMCA2 (P51531)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: SMARCA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	22439931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 457 Hs			1 1590
+	Hs
		846783 SSXT_HUMAN (1-379): 1.01e-69: 229: 87.81		SMCA2_HUMAN (1-1590): 0: 1088: 100.00
+	Hs
		60096 A4PIV9_HUMAN (1-457): 1.41e-102: 316: 87.91		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		60089 A4PIV7_HUMAN (1-457): 2.94e-101: 313: 85.25		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		257458 CREST_HUMAN (1-379): 3.56e-55: 190: 46.94		SMCA2_HUMAN (1-1590): 0: 1088: 100.00
+	Hs
		846785 SSX2_HUMAN (350-457): 6.05e-47: 162: 78.90		SMCA2_HUMAN (1-1590): 0: 1088: 100.00
+	Mm
		1150290 CREST_MOUSE (1-400): 8.25e-57: 194: 47.25		SMCA2_MOUSE (1-1590): 0: 1055: 94.38
+	Rn
		88986 D4ABC5_RAT (1-332): 5.77e-74: 240: 86.15		SMCA4_RAT (40-1588): 0: 986: 72.87
+	Mm
		1111934 SSXT_MOUSE (1-379): 1.71e-73: 239: 83.90		SMCA4_MOUSE (40-1588): 0: 986: 72.81
+	Hs
		846890 S18L2_HUMAN (1-73): 8.99e-36: 128: 52.06		SMCA2_HUMAN (1-1590): 0: 1088: 100.00
+	Hs
		846980 SSXT_HUMAN (1-379): 1.01e-69: 229: 87.81		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Mm
		1111948 CREST_MOUSE (1-400): 8.25e-57: 194: 47.25		SMCA4_MOUSE (40-1588): 0: 986: 72.81
+	Hs
		257459 CREST_HUMAN (1-379): 3.56e-55: 190: 46.94		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		60097 A4PIW0_HUMAN (1-457): 1.08e-102: 315: 100.00		SMCA5_HUMAN (610-1584): 0: 803: 27.43
+	Hs
		847108 S18L2_HUMAN (1-73): 8.99e-36: 128: 52.06		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Mm
		57185 CHD7_MOUSE (38-435): 1.02e-14: 79.3: 17.72		SMCA4_MOUSE (40-1588): 0: 986: 72.81
+	Hs
		229409 SSXT_HUMAN (1-379): 1.01e-69: 229: 87.81		SMCA5_HUMAN (610-1584): 0: 803: 27.43
+	Hs
		229412 SSX2_HUMAN (350-457): 6.05e-47: 162: 78.90		SMCA5_HUMAN (610-1584): 0: 803: 27.43
+	At
		97299 GIF1_ARATH (13-78): 2.46e-13: 70.8: 43.94		CHR12_ARATH (332-1428): 0: 746: 34.67
+	At
		96280 GIF1_ARATH (13-78): 2.46e-13: 70.8: 43.94		SYD_ARATH (679-1264): 1.36e-155: 530: 50.75
+	At
		1150854 GIF1_ARATH (13-78): 2.46e-13: 70.8: 43.94		BRM_ARATH (701-1257): 2.61e-118: 415: 45.36