Protein: MCF2
Proto-oncogene DBL (Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein; DBL-transforming protein]

Gene: MCF2
Organism: Homo sapiens
Interactions: 21
UniProt ID: P10911

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

533815

CDC42
Cell division control protein 42 homolog

3

20

Small-scale

0.866

High

533816

RHOA
Transforming protein RhoA

3

20

Small-scale

0.866

High

533808

MCF2
Proto-oncogene DBL

1

11

Small-scale

0.724

High

533818

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.692

High

533820

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

2

Small-scale

0.618

High

413071

P53
Cellular tumor antigen p53

2

1

High-throughput

0.571

High

533810

NDKA
Nucleoside diphosphate kinase A

1

3

Small-scale

0.562

High

533817

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

5

Small-scale

0.561

High

533823

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

Small-scale

0.561

High

533812

RADI
Radixin

1

5

Small-scale

0.512

High

451108

NFL
Neurofilament light polypeptide

1

10

High-throughput

0.479

High

461072

HS90A
Heat shock protein HSP 90-alpha

1

2

Small-scale

0.479

High

533809

HSP7C
Heat shock cognate 71 kDa protein

1

3

Small-scale

0.479

High

533819

ACK1
Activated CDC42 kinase 1

1

20

Small-scale

0.479

High

134539

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

533814

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

533822

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

533821

MGAP
MAX gene-associated protein

1

3

High-throughput

0.437

High

533811

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

0

Small-scale

0.261

Low

533813

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025