Interactor 1: KALRN (O60229)
Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)
Gene: KALRN
Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17607528 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EF-hand_7~Pkinase, RhoGEF~SH3_1, SH3_1~SOS1_NGEF_PH, EF-hand_7~Spectrin, EFhand_Ca_insen~Spectrin, Spectrin~Spectrin |
| Common GO terms | GO:0005829 - cytosol GO:0070062 - extracellular exosome |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
