Interactor 1: TRIO (O75962)
Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein)
Gene: TRIO
Interactor 2: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25921289 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | I-set~LRR_8, I-set~LRRCT_2, LRR_8~Pkinase, PK_Tyr_Ser-Thr~Pkinase, PK_Tyr_Ser-Thr~SH3_1 |
| Common GO terms | GO:0005524 - ATP binding GO:0007411 - axon guidance |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025