HitPredict

Interactor 1: KRT37 (O76014)
Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7) (Keratin-37) (K37)
Gene: KRT37

Interactor 2: RUFY3 (Q7L099)
Protein RUFY3 (RUN and FYVE domain-containing protein 3) (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar)
Gene: RUFY3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 469
+	Hs
		475612 K1C19_HUMAN (100-412): 1.85e-96: 297: 49.20		RUFY3_HUMAN (1-469): 2.75e-116: 351: 100.00
+	Hs
		300686 KRT37_HUMAN (1-449): 8.02e-90: 282: 100.00		RUFY1_HUMAN (60-467): 1.53e-71: 241: 55.21
+	Hs
		227259 KRT86_HUMAN (3-446): 5.66e-94: 293: 25.89		FYCO1_HUMAN (70-465): 4.6e-62: 220: 18.32
+	Hs
		563058 K1C40_HUMAN (1-437): 1.99e-153: 443: 50.23		MYH8_HUMAN (194-466): 1.04e-09: 63.3: 12.09
+	Hs
		556936 K1C40_HUMAN (1-437): 1.99e-153: 443: 50.23		MYH7_HUMAN (48-469): 1.55e-09: 62.6: 11.11
+	Hs
		1230326 K1C40_HUMAN (1-437): 1.99e-153: 443: 50.23		MYH4_HUMAN (64-466): 4.66e-09: 61: 12.77
+	Hs
		1230311 K1C40_HUMAN (1-437): 1.99e-153: 443: 50.23		MYH2_HUMAN (73-466): 7.3e-09: 60.6: 9.90
+	Hs
		535943 K1C40_HUMAN (1-437): 1.99e-153: 443: 50.23		MYH3_HUMAN (181-465): 5.88e-09: 60.6: 11.71
+	Hs
		556859 K1C40_HUMAN (1-437): 1.99e-153: 443: 50.23		MYH1_HUMAN (64-466): 8.46e-09: 60.3: 12.29
+	Hs
		300826 KRT38_HUMAN (1-427): 1.43e-85: 271: 94.61		FYCO1_HUMAN (70-465): 4.6e-62: 220: 18.32
+	Hs
		1135584 K2C72_HUMAN (12-448): 2.02e-81: 262: 23.64		FYCO1_HUMAN (70-465): 4.6e-62: 220: 18.32
+	Hs
		773163 K1C17_HUMAN (100-415): 4.7e-97: 300: 51.90		MYH10_HUMAN (249-467): 4.92e-42: 162: 15.53
+	Hs
		300650 KRT37_HUMAN (1-449): 8.02e-90: 282: 100.00		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		772754 K1C17_HUMAN (100-415): 4.7e-97: 300: 51.90		MYH9_HUMAN (236-467): 2.44e-34: 139: 15.09
+	Hs
		67555 K1C39_HUMAN (92-446): 2.61e-110: 335: 57.26		MYH7B_HUMAN (187-466): 3.12e-11: 68: 11.57
+	Hs
		49879 A1A4E9_HUMAN (93-421): 1.61e-93: 291: 50.15		MYH1_HUMAN (64-466): 8.46e-09: 60.3: 12.29
+	Hs
		556836 K1C13_HUMAN (93-421): 1.73e-93: 291: 50.15		MYH1_HUMAN (64-466): 8.46e-09: 60.3: 12.29