Interactor 1: AP2A2 (O94973)
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene: AP2A2

Interactor 2: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 34079125, 33961781, 35271311
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adaptin_N~Adaptin_N, Alpha_adaptinC2~Alpha_adaptin_C, Alpha_adaptinC2~Alpha_adaptinC2, Alpha_adaptinC2~B2-adapt-app_C
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport
GO:0009898 - cytoplasmic side of plasma membrane
GO:0016192 - vesicle-mediated transport
and 8 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 939
Hs

1 937
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Last updated: 15 Jul 2024