HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15383276
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 347
+	Hs
		474931 VIME_HUMAN (14-466): 4.57e-114: 345: 100.00		SH3G1_HUMAN (1-347): 3.07e-80: 251: 66.03
+	Hs
		606075 DESM_HUMAN (9-465): 6.71e-138: 406: 62.20		NEBU_HUMAN (7-342): 4.29e-37: 143: 16.06
+	Hs
		570561 GFAP_HUMAN (80-465): 2.57e-132: 390: 61.40		SH3Y1_HUMAN (139-341): 4.69e-38: 140: 19.73
+	Hs
		474673 VIME_HUMAN (14-466): 4.57e-114: 345: 100.00		SRC8_HUMAN (7-343): 2.87e-51: 180: 14.49
+	Hs
		474476 VIME_HUMAN (14-466): 4.57e-114: 345: 100.00		NEBU_HUMAN (7-342): 4.29e-37: 143: 16.06
+	Hs
		474899 VIME_HUMAN (14-466): 4.57e-114: 345: 100.00		SH3Y1_HUMAN (139-341): 4.69e-38: 140: 19.73
+	Hs
		437141 K2C8_HUMAN (79-461): 1.5e-139: 411: 35.51		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		606119 DESM_HUMAN (9-465): 6.71e-138: 406: 62.20		ITSN1_HUMAN (185-345): 1.53e-10: 64.6: 12.65
+	Hs
		833356 PERI_HUMAN (7-462): 7.68e-130: 385: 58.08		SRBS1_HUMAN (169-342): 1.17e-13: 74.1: 17.65
+	Hs
		570396 GFAP_HUMAN (80-465): 2.57e-132: 390: 61.40		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		570433 GFAP_HUMAN (80-465): 2.57e-132: 390: 61.40		ITSN1_HUMAN (185-345): 1.53e-10: 64.6: 12.65
+	Hs
		833287 PERI_HUMAN (7-462): 7.68e-130: 385: 58.08		SH319_HUMAN (291-342): 6.84e-09: 59.3: 48.08
+	Hs
		474948 VIME_HUMAN (14-466): 4.57e-114: 345: 100.00		SRBS1_HUMAN (169-342): 1.17e-13: 74.1: 17.65
+	Hs
		474606 VIME_HUMAN (14-466): 4.57e-114: 345: 100.00		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		987535 KRT83_HUMAN (5-418): 4.91e-92: 289: 31.34		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		987642 KRT81_HUMAN (4-411): 1.67e-91: 288: 32.28		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		987536 KRT85_HUMAN (2-418): 4.72e-91: 287: 31.59		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		987749 K2C73_HUMAN (5-414): 1.34e-90: 287: 32.10		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		227210 KRT86_HUMAN (4-418): 2.62e-90: 284: 31.74		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		451166 NFL_HUMAN (82-413): 4.6e-87: 278: 51.80		ITSN1_HUMAN (185-345): 1.53e-10: 64.6: 12.65