HitPredict

Interactor 1: AP2A2 (O94973)
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene: AP2A2

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33513601
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding GO:0030667 - secretory granule membrane GO:0031410 - cytoplasmic vesicle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 939 Hs			1 191
+	Hs
		302131 AP2A2_HUMAN (1-939): 0: 884: 100.00		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		302128 AP2A2_HUMAN (1-939): 0: 884: 100.00		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		302129 AP2A2_HUMAN (1-939): 0: 884: 100.00		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		302099 AP2A2_HUMAN (1-939): 0: 884: 100.00		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		321526 AP2A1_HUMAN (1-939): 0: 832: 78.47		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Hs
		925170 AP2B1_HUMAN (36-933): 0: 607: 16.62		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		925231 AP1B1_HUMAN (36-934): 0: 606: 17.35		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		545310 AP2B1_HUMAN (36-933): 0: 607: 16.62		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		150197 AP3D1_HUMAN (11-478): 3.33e-33: 140: 23.51		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73