HitPredict

Interactor 1: SYUG (O76070)
Gamma-synuclein (Breast cancer-specific gene 1 protein) (Persyn) (Synoretin) (SR)
Gene: SNCG

Interactor 2: GRK5 (P34947)
G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)
Gene: GRK5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10852916
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 127 Hs			1 590
+	Hs
		761956 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		GRK5_HUMAN (1-590): 0: 560: 100.00
+	Hs
		762007 SYUB_HUMAN (1-100): 4.61e-31: 109: 62.00		GRK5_HUMAN (1-590): 0: 560: 100.00
+	Hs
		302698 SYUG_HUMAN (1-127): 6.66e-35: 118: 100.00		GRK6_HUMAN (1-558): 0: 536: 72.27
+	Hs
		791157 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		GRK6_HUMAN (1-558): 0: 536: 72.27
+	Hs
		846750 SYUB_HUMAN (1-100): 4.61e-31: 109: 62.00		GRK6_HUMAN (1-558): 0: 536: 72.27
+	Hs
		733726 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		GRK4_HUMAN (1-557): 9.19e-169: 493: 68.04
+	Hs
		302706 SYUG_HUMAN (1-127): 6.66e-35: 118: 100.00		GRK1_HUMAN (3-537): 1.1e-156: 462: 47.41
+	Hs
		791413 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		GRK1_HUMAN (3-537): 1.1e-156: 462: 47.41
+	Hs
		1154619 SYUB_HUMAN (1-100): 4.61e-31: 109: 62.00		GRK1_HUMAN (3-537): 1.1e-156: 462: 47.41
+	Hs
		774819 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		ARBK2_HUMAN (2-554): 1.5e-145: 438: 34.69
+	Hs
		669110 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		ARBK1_HUMAN (2-554): 1.34e-143: 433: 35.04
+	Hs
		728072 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		AKT1_HUMAN (67-517): 4.69e-145: 429: 29.35
+	Hs
		728261 SYUB_HUMAN (1-100): 4.61e-31: 109: 62.00		AKT1_HUMAN (67-517): 4.69e-145: 429: 29.35
+	Hs
		603191 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		KPCA_HUMAN (38-509): 6.48e-141: 425: 25.52
+	Hs
		791307 SYUA_HUMAN (1-107): 1.94e-31: 110: 62.73		KPCE_HUMAN (85-503): 4.72e-137: 417: 30.30