Protein: POTE1
Protection of telomeres protein 1 (hPot1) (POT1-like telomere end-binding protein)

Gene: POTE1, POT1
Organism: Homo sapiens
Interactions: 229
UniProt ID: Q9NUX5

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0000783 - nuclear telomere cap complex
GO:0005654 - nucleoplasm
GO:0007004 - telomere maintenance via telomerase
GO:0010521 - telomerase inhibitor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1284363

ACD
Adrenocortical dysplasia protein homolog

12

3

Small-scale

0.763

High

1075013

TERF2
Telomeric repeat-binding factor 2

8

1

Small-scale

0.755

High

869758

TERF1
Telomeric repeat-binding factor 1

6

1

Small-scale

0.733

High

1311253

TINF2
TERF1-interacting nuclear factor 2

11

0

Small-scale

0.728

High

1346246

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

6

0

Small-scale

0.706

High

1346260

COF2
Cofilin-2

3

3

High-throughput

0.597

High

1346243

POTE1
Protection of telomeres protein 1

1

0

Small-scale

0.586

High

154639

TPP1
Tripeptidyl-peptidase 1

2

1

Small-scale

0.570

High

984667

CALD1
Caldesmon

2

1

High-throughput

0.561

High

749889

BRCA1
Breast cancer type 1 susceptibility protein

2

0

Small-scale

0.559

High

452284

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.543

High

1283526

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.543

High

1310372

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.543

High

1346266

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

0

High-throughput

0.543

High

295304

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.541

High

1075817

CIP4
Cdc42-interacting protein 4

1

3

High-throughput

0.541

High

1346255

DD19B
ATP-dependent RNA helicase DDX19B

1

2

High-throughput

0.541

High

1346256

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.541

High

1346259

NUDC
Nuclear migration protein nudC

1

1

High-throughput

0.541

High

211429

ST1B1
Sulfotransferase 1B1

1

2

High-throughput

0.518

High

427676

ANXA2
Annexin A2

1

1

High-throughput

0.518

High

676768

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

1

High-throughput

0.518

High

1292808

PAGE5
P antigen family member 5

1

2

High-throughput

0.518

High

1309885

ST4A1
Sulfotransferase 4A1

1

2

High-throughput

0.518

High

1315997

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

2

High-throughput

0.518

High

117456

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.518

High

201877

HXA3
Homeobox protein Hox-A3

1

0

High-throughput

0.518

High

213746

ENSA
Alpha-endosulfine

1

0

High-throughput

0.518

High

254938

CPNE3
Copine-3

1

0

High-throughput

0.518

High

274860

PALM
Paralemmin-1

1

0

High-throughput

0.518

High

324646

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.518

High

438560

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.518

High

445560

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.518

High

577508

IL1RA
Interleukin-1 receptor antagonist protein

1

0

High-throughput

0.518

High

669479

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.518

High

827284

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.518

High

837574

HNMT
Histamine N-methyltransferase

1

0

High-throughput

0.518

High

892066

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.518

High

962991

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.518

High

991899

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

High-throughput

0.518

High

1204237

F131B
Protein FAM131B

1

0

High-throughput

0.518

High

1218103

ARI3B
AT-rich interactive domain-containing protein 3B

1

0

High-throughput

0.518

High

1346244

ANM7
Protein arginine N-methyltransferase 7

1

0

High-throughput

0.518

High

1346247

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

1

0

High-throughput

0.518

High

1346263

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.518

High

157086

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.513

High

524035

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.513

High

780991

ID1
DNA-binding protein inhibitor ID-1

1

0

High-throughput

0.513

High

944459

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.513

High

1333320

DCR1B
5' exonuclease Apollo

1

0

High-throughput

0.513

High

126306

ST1C2
Sulfotransferase 1C2

1

2

High-throughput

0.494

High

334296

LDHA
L-lactate dehydrogenase A chain

1

1

High-throughput

0.494

High

422108

LDHB
L-lactate dehydrogenase B chain

1

1

High-throughput

0.494

High

428641

INVO
Involucrin

1

1

High-throughput

0.494

High

451797

ANXA4
Annexin A4

1

1

High-throughput

0.494

High

618185

COF1
Cofilin-1

1

3

High-throughput

0.494

High

654063

MAP4
Microtubule-associated protein 4

1

1

High-throughput

0.494

High

737570

PGM1
Phosphoglucomutase-1

1

1

High-throughput

0.494

High

905168

1433G
14-3-3 protein gamma

1

1

High-throughput

0.494

High

933994

TBB4B
Tubulin beta-4B chain

1

1

High-throughput

0.494

High

1046597

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.494

High

1052163

MAP7
Ensconsin

1

1

High-throughput

0.494

High

1060067

LASP1
LIM and SH3 domain protein 1

1

2

High-throughput

0.494

High

1078497

TOM34
Mitochondrial import receptor subunit TOM34

1

1

High-throughput

0.494

High

1085079

DREB
Drebrin

1

1

High-throughput

0.494

High

1152320

TWF2
Twinfilin-2

1

3

High-throughput

0.494

High

1187991

PAGE2
P antigen family member 2

1

2

High-throughput

0.494

High

1261423

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.494

High

1291755

PGM2
Phosphopentomutase

1

1

High-throughput

0.494

High

1292804

XAGE2
X antigen family member 2

1

2

High-throughput

0.494

High

1346254

DBNL
Drebrin-like protein

1

4

High-throughput

0.494

High

1346257

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

2

High-throughput

0.494

High

984539

KPCD
Protein kinase C delta type

1

0

High-throughput

0.493

High

1206203

HORN
Hornerin

1

1

High-throughput

0.489

High

483770

HS71A
Heat shock 70 kDa protein 1A

1

0

High-throughput

0.484

High

1102021

CTC1
CST complex subunit CTC1

1

1

Small-scale

0.481

High

1137578

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.481

High

1332183

STN1
CST complex subunit STN1

1

1

Small-scale

0.481

High

134222

DDX3X
ATP-dependent RNA helicase DDX3X

1

1

High-throughput

0.479

High

181740

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

1

High-throughput

0.479

High

636428

DNJB1
DnaJ homolog subfamily B member 1

1

1

High-throughput

0.479

High

1019143

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1056999

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.479

High

1346262

TR150
Thyroid hormone receptor-associated protein 3

1

1

High-throughput

0.479

High

1122126

Q549N0
Cofilin-2

1

3

High-throughput

0.470

High

278549

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.460

High

931895

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.460

High

1170309

ZBT49
Zinc finger and BTB domain-containing protein 49

1

0

High-throughput

0.460

High

154059

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.458

High

310098

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

0

Small-scale

0.458

High

377730

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

550985

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

613595

SFPQ
Splicing factor, proline- and glutamine-rich

1

0

High-throughput

0.458

High

759856

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

905757

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

907554

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.458

High

916909

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

918012

H4
Histone H4

1

0

High-throughput

0.458

High

1072038

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

1270808

CBP
CREB-binding protein

1

0

High-throughput

0.458

High

1299390

RBM14
RNA-binding protein 14

1

0

High-throughput

0.458

High

1316153

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.458

High

1327532

XRN2
5'-3' exoribonuclease 2

1

0

Small-scale

0.458

High

1346258

CP131
Centrosomal protein of 131 kDa

1

0

High-throughput

0.458

High

341562

TPA
Tissue-type plasminogen activator

1

1

High-throughput

0.437

High

396813

S10A8
Protein S100-A8

1

1

High-throughput

0.437

High

518566

FA5
Coagulation factor V

1

1

High-throughput

0.437

High

678515

S10A7
Protein S100-A7

1

2

High-throughput

0.437

High

1045546

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

1

High-throughput

0.437

High

1076553

TRIP6
Thyroid receptor-interacting protein 6

1

1

Small-scale

0.437

High

1192391

YTHD3
YTH domain-containing family protein 3

1

2

High-throughput

0.437

High

1262728

ATX2L
Ataxin-2-like protein

1

1

High-throughput

0.437

High

1274173

LPP
Lipoma-preferred partner

1

1

Small-scale

0.437

High

1316661

TMPSD
Transmembrane protease serine 13

1

1

High-throughput

0.437

High

1317028

YTHD1
YTH domain-containing family protein 1

1

2

High-throughput

0.437

High

1346250

DJB11
DnaJ homolog subfamily B member 11

1

1

High-throughput

0.437

High

1346267

YTHD2
YTH domain-containing family protein 2

1

2

High-throughput

0.437

High

235113

DOK2
Docking protein 2

1

0

High-throughput

0.296

High

296577

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

1

0

High-throughput

0.296

High

325550

CLIC3
Chloride intracellular channel protein 3

1

0

High-throughput

0.296

High

795844

MAGA4
Melanoma-associated antigen 4

1

0

High-throughput

0.296

High

809649

3HAO
3-hydroxyanthranilate 3,4-dioxygenase

1

0

High-throughput

0.296

High

841483

BPL1
Biotin--protein ligase

1

0

High-throughput

0.296

High

930545

TYB10
Thymosin beta-10

1

0

High-throughput

0.296

High

963105

PDE1B
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

1

0

High-throughput

0.296

High

976306

KIME
Mevalonate kinase

1

0

High-throughput

0.296

High

1018196

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

0

High-throughput

0.296

High

1131277

PHYD1
Phytanoyl-CoA dioxygenase domain-containing protein 1

1

0

High-throughput

0.296

High

1162409

CNST
Consortin

1

0

High-throughput

0.296

High

1203386

PRSR2
Proline and serine-rich protein 2

1

0

High-throughput

0.296

High

1217011

AT2L2
5-phosphohydroxy-L-lysine phospho-lyase

1

0

High-throughput

0.296

High

1263675

MADD
MAP kinase-activating death domain protein

1

0

High-throughput

0.296

High

1283709

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.296

High

1306459

GPA33
Cell surface A33 antigen

1

0

High-throughput

0.296

High

1313425

CCD32
Coiled-coil domain-containing protein 32

1

0

High-throughput

0.296

High

1314732

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.296

High

1342779

INO1
Inositol-3-phosphate synthase 1

1

0

High-throughput

0.296

High

1346248

SOX
Peroxisomal sarcosine oxidase

1

0

High-throughput

0.296

High

1087115

H2A2C
Histone H2A type 2-C

1

0

Small-scale

0.292

High

150080

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.282

High

207524

RGS14
Regulator of G-protein signaling 14

1

0

High-throughput

0.282

High

208225

DNPH1
5-hydroxymethyl-dUMP N-hydrolase

1

0

High-throughput

0.282

High

208299

DCX
Neuronal migration protein doublecortin

1

0

High-throughput

0.282

High

211677

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.282

High

246311

NOL3
Nucleolar protein 3

1

0

High-throughput

0.282

High

275944

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.282

High

282784

SYUG
Gamma-synuclein

1

0

High-throughput

0.282

High

311394

6PGL
6-phosphogluconolactonase

1

0

High-throughput

0.282

High

311874

TRI16
Tripartite motif-containing protein 16

1

0

High-throughput

0.282

High

331096

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.282

High

334375

AL1A1
Aldehyde dehydrogenase 1A1

1

0

High-throughput

0.282

High

382161

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.282

High

408939

K1C18
Keratin, type I cytoskeletal 18

1

0

High-throughput

0.282

High

426971

FES
Tyrosine-protein kinase Fes/Fps

1

0

High-throughput

0.282

High

447708

ENOG
Gamma-enolase

1

0

High-throughput

0.282

High

450946

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.282

High

519278

KCRB
Creatine kinase B-type

1

0

High-throughput

0.282

High

563866

ZNF32
Zinc finger protein 32

1

0

High-throughput

0.282

High

612153

CRYGS
Gamma-crystallin S

1

0

High-throughput

0.282

High

617909

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.282

High

618723

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.282

High

660726

GRN
Progranulin

1

0

High-throughput

0.282

High

685051

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.282

High

785676

ECI1
Enoyl-CoA delta isomerase 1, mitochondrial

1

0

High-throughput

0.282

High

802749

CRK
Adapter molecule crk

1

0

High-throughput

0.282

High

819545

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.282

High

829419

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.282

High

840328

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.282

High

854834

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.282

High

876911

NP1L1
Nucleosome assembly protein 1-like 1

1

0

High-throughput

0.282

High

888221

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.282

High

910080

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.282

High

945829

MT1X
Metallothionein-1X

1

0

High-throughput

0.282

High

964805

AMPD2
AMP deaminase 2

1

0

High-throughput

0.282

High

966782

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.282

High

968659

TAGL
Transgelin

1

0

High-throughput

0.282

High

969565

CX6A2
Cytochrome c oxidase subunit 6A2, mitochondrial

1

0

High-throughput

0.282

High

975202

ACY1
Aminoacylase-1

1

0

High-throughput

0.282

High

991177

TISB
mRNA decay activator protein ZFP36L1

1

0

High-throughput

0.282

High

999681

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.282

High

1019288

IFRD2
Interferon-related developmental regulator 2

1

0

High-throughput

0.282

High

1050943

DPYL3
Dihydropyrimidinase-related protein 3

1

0

High-throughput

0.282

High

1053473

GAMT
Guanidinoacetate N-methyltransferase

1

0

High-throughput

0.282

High

1058915

GNMT
Glycine N-methyltransferase

1

0

High-throughput

0.282

High

1100256

MICA
MHC class I polypeptide-related sequence A

1

0

High-throughput

0.282

High

1161354

ZN790
Zinc finger protein 790

1

0

High-throughput

0.282

High

1215928

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

1

0

High-throughput

0.282

High

1217277

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

0

High-throughput

0.282

High

1234038

AF1L2
Actin filament-associated protein 1-like 2

1

0

High-throughput

0.282

High

1243520

DP13B
DCC-interacting protein 13-beta

1

0

High-throughput

0.282

High

1286903

NXNL1
Nucleoredoxin-like protein 1

1

0

High-throughput

0.282

High

1295738

PDLI2
PDZ and LIM domain protein 2

1

0

High-throughput

0.282

High

1304282

GA2L1
GAS2-like protein 1

1

0

High-throughput

0.282

High

1309979

CPPED
Serine/threonine-protein phosphatase CPPED1

1

0

High-throughput

0.282

High

1311572

CCM2
Cerebral cavernous malformations 2 protein

1

0

High-throughput

0.282

High

1312265

ZBED2
Zinc finger BED domain-containing protein 2

1

0

High-throughput

0.282

High

1312398

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.282

High

1330601

RBSK
Ribokinase

1

0

High-throughput

0.282

High

1331049

E41L1
Band 4.1-like protein 1

1

0

High-throughput

0.282

High

1335462

CP4FB
Cytochrome P450 4F11

1

0

High-throughput

0.282

High

1343294

RTN4
Reticulon-4

1

0

High-throughput

0.282

High

1346245

DPP3
Dipeptidyl peptidase 3

1

0

High-throughput

0.282

High

1346249

NCDN
Neurochondrin

1

0

High-throughput

0.282

High

1346251

BIN2
Bridging integrator 2

1

0

High-throughput

0.282

High

1346253

EVL
Ena/VASP-like protein

1

0

High-throughput

0.282

High

1346261

GPR52
G-protein coupled receptor 52

1

0

High-throughput

0.282

High

1346264

3BP1
SH3 domain-binding protein 1

1

0

High-throughput

0.282

High

1346265

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.282

High

324071

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

873879

IF5
Eukaryotic translation initiation factor 5

1

0

High-throughput

0.279

Low

1134437

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

1173109

FBX50
F-box only protein 50

1

0

High-throughput

0.279

Low

1184579

RSRC2
Arginine/serine-rich coiled-coil protein 2

1

0

High-throughput

0.279

Low

1239795

AVL9
Late secretory pathway protein AVL9 homolog

1

0

High-throughput

0.279

Low

1183574

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.261

Low

68703

CB074
Uncharacterized protein C2orf74

1

0

High-throughput

0.251

Low

678309

COR1A
Coronin-1A

1

0

High-throughput

0.251

Low

1058986

MVP
Major vault protein

1

0

High-throughput

0.251

Low

1343901

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.251

Low

1346252

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.251

Low

1346268

LAMC3
Laminin subunit gamma-3

1

0

High-throughput

0.251

Low

603248

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

High-throughput

0.249

Low

708129

ABCD1
ATP-binding cassette sub-family D member 1

1

0

High-throughput

0.249

Low

1048045

CYLC2
Cylicin-2

1

0

High-throughput

0.249

Low

1133999

CFA58
Cilia- and flagella-associated protein 58

1

0

High-throughput

0.249

Low

1139563

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

1232798

RGF1C
Ras-GEF domain-containing family member 1C

1

0

High-throughput

0.249

Low

1297004

SNX22
Sorting nexin-22

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024