Protein: GRK4
G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)

Gene: GRK4
Organism: Homo sapiens
Interactions: 31
UniProt ID: P32298

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

733728

GRK6
G protein-coupled receptor kinase 6

3

17

High-throughput

0.855

High

733727

FRK
Tyrosine-protein kinase FRK

1

17

High-throughput

0.691

High

733731

DGKE
Diacylglycerol kinase epsilon

1

15

High-throughput

0.691

High

733735

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.691

High

458295

ADRB2
Beta-2 adrenergic receptor

1

9

Small-scale

0.647

High

663514

FSHR
Follicle-stimulating hormone receptor

1

18

Small-scale

0.647

High

461193

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

468115

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

733740

NEMO
NF-kappa-B essential modulator

1

17

High-throughput

0.561

High

193753

PER1
Period circadian protein homolog 1

1

7

High-throughput

0.536

High

402866

ANXA1
Annexin A1

1

5

High-throughput

0.536

High

713335

SPB3
Serpin B3

1

2

High-throughput

0.536

High

724536

S10A7
Protein S100-A7

1

5

High-throughput

0.536

High

730411

1433S
14-3-3 protein sigma

1

20

High-throughput

0.536

High

730997

STIP1
Stress-induced-phosphoprotein 1

1

9

High-throughput

0.536

High

733730

SPB4
Serpin B4

1

3

High-throughput

0.536

High

733733

MTA1
Metastasis-associated protein MTA1

1

1

High-throughput

0.536

High

733734

CKAP5
Cytoskeleton-associated protein 5

1

7

High-throughput

0.536

High

261103

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.513

High

733736

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.513

High

733738

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

733729

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

15

High-throughput

0.501

High

163713

TCRG1
Transcription elongation regulator 1

1

3

High-throughput

0.489

High

615333

SON
Protein SON

1

4

High-throughput

0.489

High

733726

SYUA
Alpha-synuclein

1

15

High-throughput

0.481

High

209488

SERA
D-3-phosphoglycerate dehydrogenase

1

2

Small-scale

0.479

High

733732

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.479

High

75657

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

69479

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

733737

TRM61
tRNA

1

0

High-throughput

0.279

Low

733739

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025